Pd56-11 Development of Convective Water Vapor Energy for Treating Localized Prostate Cancer: First-in-Man Early Clinical Experiences.

Dixon, Christopher; Lay, Ramon Rodriguez; Cabanas, Cesar; Rijo, Edwin; Larson, Thayne R.

doi:10.1016/j.juro.2017.02.2600

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Convective water vapor is another ablative technique that is currently used to treat BPH by delivering thermal energy transurethrally to the central and peripheral zones of the prostate (108). After histological inspection, this energy has been shown to cause necrosis in the targeted lesions and a preliminary study with short (6 months) follow up has shown this to eliminate cancer both on confirmatory biopsy and mpMRI (109,110). Gold particles with ablation have been trialed in clinic as well, with the goal of selective uptake and heating of the tumor tissues, but peer reviewed results are pending.…”

Section: Other Therapiesmentioning

confidence: 99%

“Super-active surveillance”: MRI ultrasound fusion biopsy and ablation for less invasive management of prostate cancer

et al. 2018

View full text Add to dashboard Cite

Multiparametric magnetic resonance imaging (mpMRI) of the prostate has allowed clinicians to better visualize and target suspicious lesions during biopsy. Targeted prostate biopsies give a more accurate representation of the true cancer volume and stage so that appropriate treatment or active surveillance can be selected. Advances in technology have led to the development of MRI and ultrasound fusion platforms used for targeted biopsies, monitoring cancer progression, and more recently for the application of focal therapy. Lesions visualized on mpMRI can be targeted for ablation with a variety of energy sources employed under both local and general anesthesia. Focal ablation may offer an alternative option for treating prostate cancer as compared to the well-established interventions of whole-gland radiation or prostatectomy. Focal ablation may also be an option for patients on active surveillance who wish to be even more "active" in their surveillance. In this review, we describe the advancements and development of fusion biopsies, the rationale behind focal therapy, and introduce focal ablative techniques for indolent prostate cancers ("super-active surveillance"), including cryoablation and focal laser ablation (FLA) and the subsequent MRI/biopsy surveillance.

show abstract

Section: Other Therapiesmentioning

confidence: 99%