Abstract:INTRODUCTION AND OBJECTIVE: Ultrasound (US) is mostly used for diagnostic purpose but could be used for cancer treatments if the US intensity or frequency fits to such purpose. Prostate cancer (PC) has the highest prevalence in the urological field, but indications of immune checkpoint inhibitors (ICI) for PC are limited to very few cases. Therefore, we verified the antitumor effect of US irradiation alone and the combined use of US and ICI in vitro and in vivo.METHODS: Human-derived PC cell line LNCaP and PC-… Show more
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