Pd(ii)-catalyzed cascade annulation of N-substituted anilines with CO, NH₄OAc and aldehydes to N1-substituted 2,3-dihydroquinazolin-4(1H)-ones

Abstract

N1-substituted 2,3-dihydroquinazolin-4(1H)-ones have been synthesized via Pd-catalyzed annulation of N-substituted anilines with CO, NH4OAc and aldehydes, and the reaction features simple raw materials, high step economy, and good product diversity.