2024
DOI: 10.1039/d4qo00082j
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Pd((R)-DTBM-SEGphos)Cl2-catalyzed kinetic resolution of tertiary propargylic alcohols

Jie Wang,
Wei-Feng Zheng,
Yuling Li
et al.

Abstract: We report here an asymmetry carboxylation reaction based kinetic resolution of tertiary propargylic alcohols by identifying Pd((R)-DTBM-SEGphos)Cl2 as the pre-catalyst. A variety of optically active tertiary propargylic alcohols and tetrasubstituted...

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