“…With these modifications,3 -phenylpropyl (10)a nd n-octyl (11)m igrating groups were tolerated, as was asilyl ether (12). Ther eaction was also effective with cyclic substrates,including cyclopentyl (13), cyclohexyl (14), and N-Boc-protected piperidine (15) migrating groups.Migrating groups bearing potentially sensitive functional groups such as am onosubstituted olefin (16), amide (17), ester (18), or acetal (19)were also well-tolerated in this reaction. While examples in Table 2s uggest that the reaction is effective with Grignard-derived "ate" complexes, it should be noted that alkyllithium derived "ate" complexes often offer superior reactivity such that catalyst loading can be reduced to 1mol %Pd, with many substrates still achieving complete conversion in one hour (10)(11)(12).…”