Pd-Catalyzed Aerobic Synthesis of Allylic Sulfones from Allylic Alcohols and Sulfonyl Hydrazines in Water
Jing Yu,
Xiaoyu Yan,
Yuying Chen
et al.
Abstract:A mild and green synthesis of allylic sulfones from allylic alcohols and sulfonyl hydrazines was developed in water media. The simple and commercially available Pd(PPh 3 ) 4 is used as the best catalyst, and the reaction can proceed smoothly at 40 °C under air. This new method does not require the common nitrogen protection and organic media, and can be readily scaled up in gram scale, showing the good practicality value.
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