Pd/C–Al–water facilitated selective reduction of a broad variety of functional groups

Abstract

The chemoselective reduction of a broad variety of functional groups by a Pd/C–Al–H2O system is described.

Development of the Applications of Palladium on Charcoal in Organic Synthesis

“…Additional future applications of Pd/C are expected to focus on sustainable chemistry development, because this research area remains a fateful domain for the progress of synthesis and process understanding. Thus, it is consequently expected that organic chemists will provide even more attention to Pd/C or other heterogeneous Pd catalysis systems particularly in water, in order to satisfy the demand for more eco‐compatible procedures. This approach would obviously greatly contribute to establish ‘green chemistry’.…”

Selective Synthesis of Symmetrical Secondary Amines from Nitriles with a Pt−CuFe/Fe3O4 Catalyst and Ammonia Borane as Hydrogen Donor

“…Jiao's group reported a 5NiO−Pd/SiC catalyst for the hydrogenation of nitriles with H 2 to secondary amines by the modification of NiO nanodots . Direct hydrogenation usually requires pressurized hydrogen or ultralong reaction time, which produce the hydrogenolysis by‐products . Avoiding the explosive nature of hydrogen, catalytic transfer hydrogen has the advantages of the milder reaction condition and the more practical operation .…”

Monodisperse CuPt alloy nanoparticles assembled on reduced graphene oxide as catalysts in the transfer hydrogenation of various functional organic groups

“…However, the conventional DH reactions are often conducted in elaborated reactors under pressurized hydrogen gas and high temperature in the presence of transition metal‐based catalysts, which makes them unpractical to apply in regular research laboratories . On the other hand, in order to minimize or eliminate wastes, the use of environmentally benign reagents and solvents become a hot topic environmental issue for the growing concern of safety and sustainability in green chemistry concept . In this respect, transfer hydrogenation (TH) reactions comprising the generation of hydrogen gas in situ from suitable hydrogen donor molecules and transfer of the generated hydrogen to substrates via the help of metal catalysts have been emerged as an attractive alternative to DH reactions.…”

“…[3] On the other hand, in order to minimize or eliminate wastes, the use of environmentally benign reagents and solvents become a hot topic environmental issue for the growing concern of safety and sustainability in green chemistry concept. [4] In this respect, transfer hydrogenation (TH) reactions comprising the generation of hydrogen gas in situ from suitable hydrogen donor molecules and transfer of the generated hydrogen to substrates via the help of metal catalysts have been emerged as an attractive alternative to DH reactions. Moreover, TH has recently become a popular topic in synthetic organic chemistry/catalysis and it is well-documented by several comprehensive review articles in the literature.…”