PD-1/PD-L1 inhibitors combined with chemotherapy in the treatment of thymic carcinoma metastasis to the liver

Abstract

Epithelial neoplasms of the thymus is a relatively rare malignancy. In this report, we present a case of thymic carcinoma of a 68-yearold man with hepatic metastasis, which with the severe hypokalemia, hypoproteinemia, and fatigue of concomitant symptom. After positive symptomatic treatment such as correction of electrolyte disorder, supplementation of albumin and nutritional support, the patient’s general condition recovered and improved. Then, we reviewed the literature on the treatment of thymic carcinoma, and decided to use immunotherapy combined with chemotherapy to treat this case of advanced thymic squamous carcinoma, expecting to have a good efficacy and improve the progression-free and overall survival.