PCR in the Diagnosis of Viral Hepatitis

Seelig, R; Renz, Manfred; Seelig, H. P.

doi:10.3109/07853899209147827

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1993

2024

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Cited by 9 publications

(1 citation statement)

References 74 publications

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“…For this reason, viral RNA detection in serum, as well as in feces, has been performed through the reverse tran- scription polymerase chain reaction (RT-PCR), using primers designed for different genome regions (Seelig et al 1992, Buti et al 2001, Costa-Mattioli et al 2002.…”

mentioning

confidence: 99%

Prevalence of hepatitis A virus infection in Goiânia, Goiás, Brazil, by molecular and serological procedures, 1995-2002

Fiaccadori¹,

Soares

Borges³

et al. 2006

Mem. Inst. Oswaldo Cruz

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mentioning

confidence: 99%

Prevalence of hepatitis A virus infection in Goiânia, Goiás, Brazil, by molecular and serological procedures, 1995-2002

Fiaccadori¹,

Soares

Borges³

et al. 2006

Mem. Inst. Oswaldo Cruz

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Anti-HCV-Prävalenz bei Kindern mit Blutgerinnungsstörungen

Klarmann¹,

Kreuz²,

Auerswald³

et al. 1993

23. Hämophilie-Symposion

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Importance of the polymerase chain reaction in the study of hepatitis C virus infection

1993

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Recently, the principal etiological agent of parenterally transmitted non-A, non-B hepatitis was molecularly cloned from the plasma of an experimentally infected chimpanzee and has been named hepatitis C virus. Determination of the complete nucleotide sequence of the hepatitis C virus genome was a crucial step in preparing the way for future study of this medically important human pathogen. Due to the very low concentration of virus in serum, amplification of viral RNA sequences by reverse transcription and polymerase chain reaction is the only practical method currently available for demonstrating viremia in patients with hepatitis C virus infection. This review examines the pivotal role of the polymerase chain reaction in understanding the biology of hepatitis C virus.

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PCR in the Diagnosis of Viral Hepatitis

Cited by 9 publications

References 74 publications

Prevalence of hepatitis A virus infection in Goiânia, Goiás, Brazil, by molecular and serological procedures, 1995-2002

Prevalence of hepatitis A virus infection in Goiânia, Goiás, Brazil, by molecular and serological procedures, 1995-2002

Anti-HCV-Prävalenz bei Kindern mit Blutgerinnungsstörungen

Importance of the polymerase chain reaction in the study of hepatitis C virus infection

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