Abstract:Objectives: This study aimed to evaluate the long-term economic benefits of Alectinib versus Crizotinib in first-line treatment for anaplastic lymphoma kinase-positive (ALK+) advanced non-small cell lung cancer (NSCLC) from a China societal perspective. Methods: A Markov model was developed using partition survival methods and three health states: progression-free survival (PFS), post-progression survival (PPS), and death. Survival data were derived from ALEX trial, and parametric survival functions were selec… Show more
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