PC-Fix and local infection resistance – Influence of implant design on postoperative infection development, clinical and experimental results

Eijer, Henk; Hauke, Chr.; Arens, S.; Printzen, Gert; Schlegel, U.; Perren, Stephan M.

doi:10.1016/s0020-1383(01)00124-3

Cited by 52 publications

(34 citation statements)

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“…One reason that implant design (i.e. DCP versus LCP) can reduce infection rates is believed to be due to the fact that infection can spreads along any contiguous area of necrosis, such as may be caused by compressing the plate onto the bone [5]. The introduction of 'biological internal fixation' for example was based on the use of locked internal fixators which protect softtissue vitality and prevent compression necrosis of the bone [21], leading to reduced infection risk.…”

Section: Discussionmentioning

confidence: 99%

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Titanium and steel fracture fixation plates with different surface topographies: Influence on infection rate in a rabbit fracture model

Metsemakers

Schmid

Zeiter

et al. 2016

Injury

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Section: Discussionmentioning

confidence: 99%

“…microrough, polished), and the type of plate (e.g. locking compression plate (LCP), dynamic compression plate (DCP)) [4][5][6].…”

Section: Introductionmentioning

confidence: 99%

Titanium and steel fracture fixation plates with different surface topographies: Influence on infection rate in a rabbit fracture model

Metsemakers

Schmid

Zeiter

et al. 2016

Injury

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“…At the same time, the locking plate structure can avoid stress shielding below the plate and reduce the need for soft tissue dissection. Thus, in theory, the locking plate can preserve periosteal blood supply, accelerate bone healing, and decrease the incidence of infection [22,23].…”

Section: Discussionmentioning

confidence: 99%

Comparison of a new minimum contact locking plate and the limited contact dynamic compression plate in an osteoporotic fracture model

Xiong

Zhao

Wang

et al. 2008

International Orthopaedics (SICOT)

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The purpose of this study was to investigate the biomechanical properties of a new minimum contact locking plate (MC-LP) compared with the limited contact dynamic compression plate (LC-DCP). Eighteen pairs of fresh human osteoporotic cadaver radii were equally divided into three groups. Each specimen was tested in each of the following force applications: anteroposterior (AP) four point bending, mediolateral (ML) four point bending, and torsion. A 10-mm gap osteotomy model was used to simulate a comminuted diaphyseal radial fracture. For each pair, one radius received a limited contact dynamic compression plate (LC-DCP) and the contralateral radius was fixed with a minimum contact locking plate (MC-LP). Specimens were tested in nondestructive four point bending and torsion on an electronic universal material testing system. The results indicate that the MC-LP system is significantly more stable than the LC-DCP system when tested in four point bending and torsion in an osteoporotic comminuted radial diaphyseal fracture model. Résumé Le but de cette étude est d'étudier les propriétés biomécaniques d'une nouvelle minimum plaque de verrouillage de contact (MC-LP) en comparant avec la plaque dynamique de compression de contact limité (LC-DCP). Dix-huit paires de rayons d'osteoporose humains frais de cadavres sont divisées en trois groupes égaux. Chaque spécimen est respectivement examiné sous les charges suivantes : quatre points courbés antéropostérieurs (AP), quatre points courbés médiolatéraux(ML), et torsion. Un modèle de jeu de fracture de 10mm est construit pour chaque spécimen, afin de simuler un modèle de fracture pulvérisée. Pour chaque paire, l'un des rayons est fixé par la plaque dynamique de compression de contact limité (LC-DCP), l'autre est fixé par une minimum plaque de verrouillage de contact (MC-LP). Une épreuve de qutre points courbés et de torsion non-déstructive des spécimens s'est fait dans un système d'essai de matériaux universels électroniques. Les résultats indiquent que dans le modèle de fracture de rayon pulvérisé d'ostéoporose, le système de MC-LP est plus stable que celui de LC-DCP.

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“…In the early 90s, at the AO Research Institute Davos, Dr Henk Eijer (clinician) and Dr Slobodan Tepic (scientist) made a very interesting observation during infection studies comparing, 1) titanium and steel (Schlegel and Perren, 2006), and 2) compression plating versus locking plating for susceptibility to infection (Eijer et al, 2001;Arens et al, 2001). Various doses of S. aureus (clinical strain) were applied to rabbits between the plate and bone to determine the ID 50 for infection.…”

Section: Rg Richardsmentioning

confidence: 99%

The implant infection paradox: why do some succeed when others fail? Opinion and discussion paper

Yue

Zhao²,

Ren³

et al. 2015

eCM

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PC-Fix and local infection resistance – Influence of implant design on postoperative infection development, clinical and experimental results

Cited by 52 publications

References 0 publications

Titanium and steel fracture fixation plates with different surface topographies: Influence on infection rate in a rabbit fracture model

Titanium and steel fracture fixation plates with different surface topographies: Influence on infection rate in a rabbit fracture model

Comparison of a new minimum contact locking plate and the limited contact dynamic compression plate in an osteoporotic fracture model

The implant infection paradox: why do some succeed when others fail? Opinion and discussion paper

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