Pb2207 Early Spleen Response Is a Good Prognostic Factor of Ruxolinib Outcome in Patients With Myelofibrosis

Abstract

CA 6.0 was used for data analysis. The results were presented as median with 95% confidence interval (CI). Mann-Whitney and Spearman rank tests were applied, the differences considered statistically significant with p < 0.05( * ). Results: 23 (63.9%) PMF patients in the study were JAK2V617F-positive, 8 (22.2%) had mutation in CALR gene. JAK2V617F allele burden data was available in 13 PMF patients with median 8.1% (95%CI 3.4-43.8%). The results of hemostatic parameters in PMF patients and controls are shown in Table 1.