Abstract:However it is known that BCR-ABL1 may persist not only in leukemic cells but in myeloid and other cells. In this case MRD determined by other methods may clarify the real status of the disease. Aims: To compare results of MRD study in Ph+ B-ALL patients performed by reverse transcription PCR (RT-PCR, BCR-ABL1) and multicolor flow cytometry (MFC). Methods: The main principle of Ph+RALL-2012 is non-intensive treatment but non-interruptive with simultaneous administration of tyrosine kinase inhibitors. Study of M… Show more
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