Many changes like increment of the population and demanded services, expansion of industries, increasing of transportation demand, etc., have increased the emission of dioxin and furan. There was no indicative research conducted on the quantification and management practices of the unintentionally produced persistent organic pollutants like dioxin and Furan. A UNEP model for dioxin-and furan-related POPs management was commonly used to assess the main anthropogenic sources of dioxin and furan. In this book chapter, UNEP toolkit that was developed in 2013 is used to identify and quantify the sector-based emission of dioxin and furan. About nine main groups of anthropogenic POPs sources such as waste incineration, open burning process, ferrous and nonferrous metal production, etc., explicitly discussed in the report were identified. The case study in Addis Ababa showed that all organizations have no awareness about the dioxin and furan emission issues and follow very weak management styles. Finally, the book chapter suggests the reformulation of the national legal management framework, adaptation of best available technology with less POPs footprint, increasing public and stakeholder's awareness and participation and capacitating the concerned government organization.