Patterns of recurrence following pelvic exenteration and external radiotherapy for locally advanced primary rectal adenocarcinoma

Abstract

Local control of locally advanced primary rectal adenocarcinoma requiring a pelvic exenteration is improved by the addition of radiotherapy. When recurrences do occur they are predominantly at extrapelvic sites.

Multivisceral resection for colon cancer

“…In contrast, series that also included patients with rectal cancer have found the uterus, small bowel, urinary bladder, and abdominal wall to be the most frequently attached organs [9]. Explanation for the previously mentioned observation may be due to exclusion of patients with rectal tumors that were previously reported [15].…”

Management of Locally Advanced Primary and Recurrent Rectal Cancer

“…79 Longterm survival with excellent local control is possible after TPE for primary locally advanced rectal cancer (Table 1). 70,72,[80][81][82][83][84][85][86][87] The majority of resections in primary cancer are without microscopic or macroscopic residual tumor mass, which clearly justifies the use of TPE in selected patients with primary disease. Although current guidelines for colorectal cancer surgery advocate TPE, only one third of the patients in a recent study based on SEER (survival, epidemiology, and end results) data underwent the appropriate surgical resection.…”

Cystoprostatectomy versus prostatectomy alone for locally advanced or recurrent pelvic cancer

“…[11][12][13] Local recurrence occurs in between 5 and 37% of primary rectal cancers, depending on the distance from the anal verge. [11][12][13] Local recurrence occurs in between 5 and 37% of primary rectal cancers, depending on the distance from the anal verge.…”