Patterns of proopiomelanotropin and proopiocortin gene expression and of immunohistochemistry for gonadotropin-releasing hormones (lGnRH-I and III) during the life cycle of a nonparasitic lamprey: Relationship to this adult life history type

Youson, John H.; Heinig, Julie A.; Khanam, S.F.; Sower, Stacia A.; Kawauchi, Hiroshi; Keeley, Fred W.

doi:10.1016/j.ygcen.2005.10.015

Cited by 14 publications

(3 citation statements)

References 52 publications

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“…Concerning GNRH, no report describes any function of this hormone in invertebrate metamorphosis. However, it is possible that GNRH may have a role in lamprey metamorphosis because, in sea lamprey, the level of GNRH increases throughout the stage of spontaneous metamorphosis (Youson and Sower, 2001;Youson et al, 2006).…”

Section: Hormone Signallingmentioning

confidence: 99%

ERK- and JNK-signalling regulate gene networks that stimulate metamorphosis and apoptosis in tail tissues of ascidian tadpoles

et al. 2007

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In ascidian tadpoles, metamorphosis is triggered by a polarized wave of apoptosis, via mechanisms that are largely unknown. We demonstrate that the MAP kinases ERK and JNK are both required for the wave of apoptosis and metamorphosis. By employing a gene-profiling-based approach, we identified the network of genes controlled by either ERK or JNK activity that stimulate the onset of apoptosis. This approach identified a gene network involved in hormonal signalling, in innate immunity, in cell-cell communication and in the extracellular matrix. Through gene silencing, we show that Ci-sushi, a cell-cell communication protein controlled by JNK activity, is required for the wave of apoptosis that precedes tail regression. These observations lead us to propose a model of metamorphosis whereby JNK activity in the CNS induces apoptosis in several adjacent tissues that compose the tail by inducing the expression of genes such as Ci-sushi.

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Section: Hormone Signallingmentioning

confidence: 99%

ERK- and JNK-signalling regulate gene networks that stimulate metamorphosis and apoptosis in tail tissues of ascidian tadpoles

et al. 2007

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“…In the parasitic phase of the sea lamprey, the distribution of GnRH has not been studied. However, it has been shown that the period of metamorphosis from larval to parasitic state is a prominent phase of up-regulated activity for hypothalamic lGnRH-I and -III corresponding to gonadal growth (Youson et al, 2006). It was postulated that based on the overlap of olfactory- and GnRH-containing fibers from prolarval stages to metamorphosis, olfactory stimuli may play a major role in the regulation of GnRH secretion in lampreys (Tobet et al, 1995).…”

Section: Discussionmentioning

confidence: 99%

Expression of three GnRH receptors in specific tissues in male and female sea lampreys Petromyzon marinus at three distinct life stages

et al. 2013

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“…The position of MCH cells in the hypothalamus is illustrated in Figure 3. The DHN is found bordering the third ventricle (3V) and is part of the paraventricular organ (PVO), an ubiquitous non-mammalian structure that contains a myriad of neuroactive substances (Nozaki et al, 1983; Brodin et al, 1990; Tobet et al, 1995), plays a role in hypothalamic integration (Vigh-Teichmann and Vigh, 1989; Meurling and Rodríguez, 1990), has no blood-brain barrier, and is highly vascularized (Röhlich and Vigh, 1967). Exclusively in sexually maturing L. petromizon , a weakly-labeled group of neurons is found in the anterior basal telencephalon.…”

Section: The Mch System In Early Chordatesmentioning

confidence: 99%

The Melanin-Concentrating Hormone (MCH) System: A Tale of Two Peptides

Diniz

Bittencourt

2019

Front. Neurosci.

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The melanin-concentrating hormone (MCH) system is a robust integrator of exogenous and endogenous information, modulating arousal and energy balance in mammals. Its predominant function in teleosts, however, is to concentrate melanin in the scales, contributing to the adaptive color change observed in several teleost species. These contrasting functions resulted from a gene duplication that occurred after the teleost divergence, which resulted in the generation of two MCH-coding genes in this clade, which acquired distinctive sequences, distribution, and functions, examined in detail here. We also describe the distribution of MCH immunoreactivity and gene expression in a large number of species, in an attempt to identify its core elements. While initially originated as a periventricular peptide, with an intimate relationship with the third ventricle, multiple events of lateral migration occurred during evolution, making the ventrolateral and dorsolateral hypothalamus the predominant sites of MCH in teleosts and mammals, respectively. Substantial differences between species can be identified, likely reflecting differences in habitat and behavior. This observation aligns well with the idea that MCH is a major integrator of internal and external information, ensuring an appropriate response to ensure the organism's homeostasis. New studies on the MCH system in species that have not yet been investigated will help us understand more precisely how these habitat changes are connected to the hypothalamic neurochemical circuits, paving the way to new intervention strategies that may be used with pharmacological purposes.

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Patterns of proopiomelanotropin and proopiocortin gene expression and of immunohistochemistry for gonadotropin-releasing hormones (lGnRH-I and III) during the life cycle of a nonparasitic lamprey: Relationship to this adult life history type

Cited by 14 publications

References 52 publications

ERK- and JNK-signalling regulate gene networks that stimulate metamorphosis and apoptosis in tail tissues of ascidian tadpoles

ERK- and JNK-signalling regulate gene networks that stimulate metamorphosis and apoptosis in tail tissues of ascidian tadpoles

Expression of three GnRH receptors in specific tissues in male and female sea lampreys Petromyzon marinus at three distinct life stages

The Melanin-Concentrating Hormone (MCH) System: A Tale of Two Peptides

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