Patterns of practice for adaptive and real-time radiation therapy (POP-ART RT) part II: Offline and online plan adaption for interfractional changes

Bertholet, Jenny; Anastasi, Gail; Noble, D.; Bel, Arjan; Leeuwen, R. Van; Roggen, Toon; Duchateau, Michaël; Pilskog, Sara; Garibaldi, Cristina; Tilly, Nina; García-Mollá, Rafael; Bonaque, J.; Oelfke, Uwe; Aznar, Marianne C.; Heijmen, B.

doi:10.1016/j.radonc.2020.06.017

Cited by 56 publications

(69 citation statements)

References 50 publications

(73 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…ART is mainly utilized and advocated for locally advanced HNSCC patients, especially those who are treated with definitive chemoradiotherapy (14,26,33,34). In the present series and in line with current literature, patients who underwent chemoradiotherapy had a statistically significant higher re-plan rate compared to sole radiotherapy.…”

Section: Discussionsupporting

confidence: 84%

Radiotherapy for Head and Neck Cancer: Evaluation of Triggered Adaptive Replanning in Routine Practice

et al. 2020

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 84%

Radiotherapy for Head and Neck Cancer: Evaluation of Triggered Adaptive Replanning in Routine Practice

et al. 2020

View full text Add to dashboard Cite

“…However, the increase in treatment time coupled with the number of staff involved at the time of treatment will limit the uptake [18]. Only 6% of adaptive treatments were delivered by online daily replanning in a recently published survey and although human resources were identified as the main barrier there was no detail regarding the professionals involved in the workflow [19]. To thoroughly investigate the potential of on-line MRIgRT wide implementation is essential.…”

Section: Introductionmentioning

confidence: 99%

International survey; current practice in On-line adaptive radiotherapy (ART) delivered using Magnetic Resonance Image (MRI) guidance

McNair

Wiseman

Joyce

et al. 2020

Technical Innovations & Patient Support in Radiation Oncolo

View full text Add to dashboard Cite

Background and purpose: The uptake of new technologies has varied internationally and there have often been barriers to implementation. On-line adaptive radiotherapy (ART) promises to improve patient outcome. This survey focuses on the implementation phase of delivering ART and professional roles and responsibilities currently involved in the workflow and changes which may be expected in the future. Materials and methods: A 38 question survey included aspects on current practice; professional responsibilities; benefits and barriers; and decision making and responsibilities. For the purposes of the questionnaire and paper, ART was considered where tumour and /or organs at risk were contoured and replanning was performed on-line. The questionnaire was electronically distributed via radiotherapy networks. Results: Nineteen international responses were received.

show abstract

“…The overall aim of these adaptive radiotherapy strategies is to further improve the fidelity of dose delivered to target in order to reliably reduce the PTV so dose to normal tissues can also be reduced. In bladder cancer radiotherapy, two main adaptive approaches based on the wide availably of cone bean CT (CBCT) have seen drift into clinical practice based on reported dosimetric gains (68,73).…”

Section: Inter-fractional Motion Mitigationmentioning

confidence: 99%

“…The alternative and more widely adopted method currently employed is to generate a library of patient specific treatment plans with varying PTV sizes (73). Using the CBCT acquired prior to each fraction, the anatomy is assessed to select the most appropriate plan that covers the bladder target with minimal normal tissue exposure.…”

Section: Inter-fractional Motion Mitigationmentioning

confidence: 99%

MR-Guided Adaptive Radiotherapy for Bladder Cancer

et al. 2021

View full text Add to dashboard Cite

Radiotherapy has an important role in the curative and palliative treatment settings for bladder cancer. As a target for radiotherapy the bladder presents a number of technical challenges. These include poor tumor visualization and the variability in bladder size and position both between and during treatment delivery. Evidence favors the use of magnetic resonance imaging (MRI) as an important means of tumor visualization and local staging. The availability of hybrid systems incorporating both MRI scanning capabilities with the linear accelerator (MR-Linac) offers opportunity for in-room and real-time MRI scanning with ability of plan adaption at each fraction while the patient is on the treatment couch. This has a number of potential advantages for bladder cancer patients. In this article, we examine the technical challenges of bladder radiotherapy and explore how magnetic resonance (MR) guided radiotherapy (MRgRT) could be leveraged with the aim of improving bladder cancer patient outcomes. However, before routine clinical implementation robust evidence base to establish whether MRgRT translates into improved patient outcomes should be ascertained.

show abstract

Patterns of practice for adaptive and real-time radiation therapy (POP-ART RT) part II: Offline and online plan adaption for interfractional changes

Cited by 56 publications

References 50 publications

Radiotherapy for Head and Neck Cancer: Evaluation of Triggered Adaptive Replanning in Routine Practice

Radiotherapy for Head and Neck Cancer: Evaluation of Triggered Adaptive Replanning in Routine Practice

International survey; current practice in On-line adaptive radiotherapy (ART) delivered using Magnetic Resonance Image (MRI) guidance

MR-Guided Adaptive Radiotherapy for Bladder Cancer

Contact Info

Product

Resources

About