Patterns of Hearing Loss Among HIV Adult Patients Attending Clinic at Tertiary Hospital, Tanzania

Massawe, Enica Richard; Moshi, Ndeserua; Kimario, John; Liyombo, Edwin; Kishevo, Perfect

doi:10.31080/asol.2022.04.0411

Cited by 2 publications

(4 citation statements)

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“…Malignant melanoma, High grade NHL, Olfactory Neuroblastoma, Plasmacytoma and Rhabdomyosarcoma were also seen in descending order among the malignant tumors in the present study A study in Tanzania showed the commonest anatomical site for head and neck cancer was the Sinonasal tract which showed the highest variation in histopathologic diagnosis with predominance of squamous cell carcinoma [14].This is in concordance with most literatures and ours where squamous cell carcinoma was the commonest but differed in the incidence of lesions following SCC like; India showing malignant melanoma as the 2 nd commonest tumor followed by Nasopharyngeal carcinoma, Adenocarcinoma followed by high grade NHL in Sri Lanka, Adenoidcystic carcinoma followed by olfactory Neuroblastoma in Rwanda, Adenocarcinoma followed by Malignant Melanoma and High grade NHL in Ghana; and Adenocarcinoma followed by Mucoepidermoid carcinoma in Nigeria [19,20,25,27,29].…”

Section: Discussionsupporting

confidence: 63%

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Histopathologic study of sinonasal lesions: A hospital based retrospective study, from January 2016 to August 2020

Ruth Abera Alemayehu,

Tufa Gemechu

2023

Int. J. Sci. Res. Updates

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Background: Sinonasal area is a host to various neoplastic and non- neoplastic lesions. The presenting symptoms of sinonasal lesions are similar and pose difficulty for diagnosis based on clinical features and advanced imaging modalities, which makes histopathology the principal diagnostic tool approach for these lesions. The aim of this study is to determine the various histopathologic types of Sinonasal lesions, their classification and relative distribution with regards to age and sex in our setting. Materials and Methods: A retrospective cross-sectional descriptive study conducted on 306 cases of sinonasal lesions over the period from January 2016 to August 2020. All the sinonasal tissues were received and diagnosed at histopathology section of Department of Pathology in Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. The Pathology reports were collected from the pathology data archives; and the variables of study were extracted by using a data extraction sheet, and data analysis was done using SPSS version 26.0. Results: Most affected age group was 21-30 years 81(26.5%). Male predominance was observed with M: F ratio of 1.4:1.Nasal cavity was the commonest anatomical site involved 237(77.5%).There were 137(44.8%) Non-neoplastic lesions and 169(55.2%) Neoplastic lesions. Inflammatory Sinonasal Polyps 100(73.0%) were the most common among non-neoplastic lesions; inverted Sinonasal Papilloma 34(41%) the most common among the benign neoplastic and squamous cell carcinoma and nasopharyngeal carcinoma accounting for 21(25.6%) cases each, were the commonest malignant lesions. Conclusion: clinical findings and advanced image modalities can reach to a presumptive diagnosis for the sinonasal lesions but histopathology remains the gold standard for categorizing and diagnosis of non-neoplastic and neoplastic lesions of sinonasal tract.

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Section: Discussionsupporting

confidence: 63%

“…These patients may have an increased acquisitions of oncogenic HPV strains at multiple anatomic sites. However, contribution of HPV to head and neck cancers is not well described in our continent [14,15,16,17].…”

Section: Statement Of the Problemmentioning

confidence: 99%

Histopathologic study of sinonasal lesions: A hospital based retrospective study, from January 2016 to August 2020

Ruth Abera Alemayehu,

Tufa Gemechu

2023

Int. J. Sci. Res. Updates

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“…12 Another study done in Tanzania by Massawe et al found that patients on ART had less prevalence of hearing loss compared to those, not on ART. 23 While other studies report that mere exposure to ART is associated with poorer hearing threshold compared to those not exposed. 15,16 In our study, on un-adjusted OR it was seen that patients on second-line ART had 2.8 times higher odds of having an abnormal HPTA and LPTA compared to those on the first line.…”

Section: Association Of Art Use With Snhlmentioning

confidence: 98%

“…These varying results reported by different studies of either no association of ART with hearing loss, higher odds of hearing loss in ART naïve patients or higher odds hearing abnormalities with ART use could be attributed to the lack of monitoring hearing status at initiation or change of ART, or few prospective cohort studies or even randomized clinical trials to find evidence of this inconsistent observation in different studies. 12,14,[23][24][25][26]…”

Section: Association Of Art Use With Snhlmentioning

confidence: 99%

Magnitude and factors associated with sensorineural hearing loss in patients with HIV/AIDS attending tertiary hospital in northern zone Tanzania

Kipiki

Mlay

Mtenga

et al. 2023

Int J Otorhinolaryngol Head Neck Surg

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Background: It is estimated that 20% to 50% of patients with HIV have hearing loss. 70% of people living with HIV worldwide are reported to be in Sub-Saharan Africa, making this region have a probable greater disease burden. However, hearing assessment is missing as a routinely conducted investigation in some treatment guidelines. The study aimed to determine the magnitude and factors associated with sensorineural hearing loss in patients with HIV/AIDS attending a tertiary hospital in Northern Tanzania. Methods: This observational hospital-based cross-sectional study was conducted at the HIV outpatient clinics. The study population comprised children and adults with HIV/AIDS aged between 7 and 60 years old. A structured questionnaire and medical files were used to obtain hearing history and relevant medical information. Tympanometry and pure-tone audiometry was done. Results: This study included 152 study participants. The median age was 46 (36.0 – 53.0) years. 109 (71.7%) were females, and 43 (28.3%) were males. The prevalence of sensorineural hearing loss (SNHL) was 34.9% (53 cases). Conductive hearing loss was 7.2% (11 cases,) and mixed hearing loss was 9.2% (14 cases). There was a statistically significant association between SNHL with nadir CD4 count, current viral load, and ART use duration of more than 10 years. Conclusions: The magnitude of SNHL in patients with HIV/AIDS is alarmingly high. Hearing status should be assessed at baseline and follow-up course of HIV/AIDS management. This will also help analyse the probable impact of ART changes in the treatment guidelines.

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Patterns of Hearing Loss Among HIV Adult Patients Attending Clinic at Tertiary Hospital, Tanzania

Cited by 2 publications

References 0 publications

Histopathologic study of sinonasal lesions: A hospital based retrospective study, from January 2016 to August 2020

Histopathologic study of sinonasal lesions: A hospital based retrospective study, from January 2016 to August 2020

Magnitude and factors associated with sensorineural hearing loss in patients with HIV/AIDS attending tertiary hospital in northern zone Tanzania

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