Patterns of acute leukaemia occurrence among children in the Chernobyl region

Abstract

Study results suggest that the increased risk of leukaemia and acute leukaemia among those children born in 1986 and resident in radioactively contaminated territories may be associated with exposure to radiation resulting from the Chernobyl accident.

Sex-specific microRNAome deregulation in the shielded bystander spleen of cranially exposed mice

“…It is known that radiation-induced cancer occurs more frequently in males, [72][73][74] yet the molecular grounds of this sex-specific bias are not well understood. The microRNA patterns observed in this study in the male and female spleen tissue may be used to further explore the molecular basis of sex differences in radiation-induced carcinogenesis.…”

Increased incidence of malignancies in Sweden after the Chernobyl accident—a promoting effect?

“…Several studies on childhood leukemia have been performed outside the former USSR [Auvinen et al, 1994;Hjalmars et al, 1994;Petridou et al, 1994;Parkin et al, 1996;Tondel et al, 1996], but none has shown any clear relationship to the fallout from the Chernobyl accident. However, exposure in utero has shown to increase the risk of leukemia significantly in Greece, Germany, and Ukraine [Petridou et al, 1996;Michaelis et al, 1997;Steiner et al, 1998;Noshchenko et al, 2001], but not in Belarus [Ivanov et al, 1998]. …”

Leukemia Following the Chernobyl Accident

“…Several ecologic studies have been reported of leukemia occurring among those exposed in utero (Petridou et al 1996;Ivanov et al 1998;Steiner et al 1998;Noshchenko et al 2001). None of these studies provide evidence for an association with leukemia with the possible exception of the Greek study (Petridou et al 1996), but in view of the ecologic nature of the studies and the generally small number of cases available for analysis, it cannot be said that this provides substantive evidence for a lack of association.…”