2016
DOI: 10.1002/gps.4464
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Patterns and persistence of behavioural and psychological symptoms in those with cognitive impairment: the importance of apathy

Abstract: van der Linde, Rianne M. and Matthews, Fiona E. and Dening, Tom and Brayne, Carol (2016) Patterns and persistence of behavioural and psychological symptoms in those with cognitive impairment: the importance of apathy. International Journal of Geriatric Psychiatry . ISSN 0885-6230Access from the University of Nottingham repository: http://eprints.nottingham.ac.uk/33569/1/VanderLinde%20IJGP%20apathy_Revised %20Paper%20-%20changes%20accepted.pdf Copyright and reuse:The Nottingham ePrints service makes this work … Show more

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Cited by 54 publications
(39 citation statements)
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“…Apathy appears early during MCI, increases in severity as the disease progresses, and tends to have a chronic course. In a population based study of older adults followed over ten years (N=3626), apathy was noted to be highly prevalent at 31.9%; and symptoms persisted for at least one year in 62% of subjects with apathy (van der Linde et al, 2016). Furthermore, the mortality rate among those with apathy was 3.1 times higher compared to those without apathy (van der Linde et al, 2016).…”
Section: Introductionmentioning
confidence: 99%
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“…Apathy appears early during MCI, increases in severity as the disease progresses, and tends to have a chronic course. In a population based study of older adults followed over ten years (N=3626), apathy was noted to be highly prevalent at 31.9%; and symptoms persisted for at least one year in 62% of subjects with apathy (van der Linde et al, 2016). Furthermore, the mortality rate among those with apathy was 3.1 times higher compared to those without apathy (van der Linde et al, 2016).…”
Section: Introductionmentioning
confidence: 99%
“…Although, there is some overlap with depressive symptoms, several groups have established apathy as a distinct entity lacking symptoms of dysphoria, suicidal ideation, self-criticism, feelings of guilt, and hopelessness (Levy et al, 1998). The prevalence of apathy in MCI has been reported to be as high as 60.5% (Ellison et al, 2008;Hwang et al, 2004;Lyketsos et al, 2002;van der Linde et al, 2016). Apathy appears early during MCI, increases in severity as the disease progresses, and tends to have a chronic course.…”
Section: Introductionmentioning
confidence: 99%
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“…Apathy contributes to a poorer quality of life and a faster rate of cognitive decline (Tierney, Woods, Weinborn, & Bucks, 2018;Yonas et al, 2014). Additionally, risk of mortality in those with apathy increases by over three times compared to those without apathy (van der Linde, Matthews, Dening, & Brayne, 2017). Those caring for people with apathy are also affected with higher carer burden reported when compared with other symptoms (Dauphinot et al, 2015;Lou et al, 2015).…”
Section: Introductionmentioning
confidence: 99%
“…Apathy in dementia is associated with a range of adverse outcomes including cognitive decline, increased risk for nursing home placement and significant distress for family caregivers (Massimo et al, 2009). Apathy also has a strong association with mortality and a negative impact on management of comorbid conditions and disability (van der Linde, Matthews, Dening, & Brayne, 2017). Passivity or "passive behavior" is a similar concept that has been studied in the field of dementia and refers to a "reduction of energy, drive and initiative.…”
Section: Introductionmentioning
confidence: 99%