“…Nuclear -catenin was reported in the corresponding pole of the Nematostella embryo (Wikramanayake et al, 2003). Finally, it has been shown that misexpression of Wnt3, frizzled (Momose et al, 2008;Momose and Houliston, 2007) and -catenin (Gee et al, 2010), as well as blocking of GSK3 (Hassel et al, 1993;Müller et al, 2004b), affects AP axis formation, suggesting that a Wnt-mediated organizer acts to specify the position of the cnidarian head (Broun et al, 2005). There is no functional data in the literature on the effect of Wnt pathway inhibition on aboral structures (Tanaka and Weidinger, 2008).…”