Patterned polymer growth on silicon surfaces using microcontact printing and surface-initiated polymerization

Jeon, Noo Li; Choi, Insung S.; Whitesides, George M.; Kim, Namyong Y.; Laibinis, Paul E.; Harada, Yoshiko; Finnie, Krista R.; Girolami, Gregory S.; Nuzzo, Ralph G.

doi:10.1063/1.125582

Cited by 159 publications

(153 citation statements)

References 23 publications

Supporting

Mentioning

150

Contrasting

Unclassified

Order By: Relevance

“…[32,33] We hypothesized that coatings of this nature would be a prerequisite for protein resistance, based on the findings of Whitesides, Grunze, and others. [6,16,34] Many polymerization mechanisms have been realized in a SIP format, including living cationic and anionic polymerization, [35,36] ring-opening metathesis polymerization, [37,38] condensation polymerization, [39,40] free-radical polymerization, [32,[41][42][43] and atom-transfer radical polymerization (ATRP). [44][45][46][47] We chose ATRP largely because it is simple to perform, affords good control of polymerization kinetics, and is compatible with a range of solvents.…”

Section: à2mentioning

confidence: 99%

In Pursuit of Zero: Polymer Brushes that Resist the Adsorption of Proteins

2009

View full text Add to dashboard Cite

Protein resistant or “non‐fouling” surfaces are of great interest for a variety of biomedical and biotechnology applications. This article briefly reviews the development of protein resistant surfaces, followed by recent research on a new methodology to fabricate non‐fouling surfaces by surface‐initiated polymerization. We show that polymer brushes synthesized by surface‐initiated polymerization that present short oligo(ethylene glycol) side chains are exceptionally resistant to protein adsorption and cell adhesion. The importance of the protein and cell resistance conferred by these polymer brushes is illustrated by their use as substrates for the fabrication of antibody microarrays that exhibit femtomolar limits of detection in complex fluids such as serum and blood with relaxed requirements for intermediate wash steps. This example highlights the important point that the reduction in background noise afforded by protein‐resistant surfaces can greatly simplify the development of ultrasensitive heterogeneous, surface‐based clinical and proteomic assays with increased sensitivity and utility.

show abstract

Section: à2mentioning

confidence: 99%

In Pursuit of Zero: Polymer Brushes that Resist the Adsorption of Proteins

2009

View full text Add to dashboard Cite

show abstract

“…The potential to form two-dimensional gradients [155][156][157] and micron-scale patterns [158][159][160][161] of initiator-substituted adsorbates, together with control of the composition of the film by block copolymerization using a variety of polymerization methods [162][163][164] and monomers, affords a high level of control over the structure and functionality of polymer brushes, which allows for tailoring of the brushes for a wide variety of applications.…”

Section: Fa8 Raynor Et Al: Controlling Cell Adhesion To Biomaterialsmentioning

confidence: 99%

Polymer brushes and self-assembled monolayers: Versatile platforms to control cell adhesion to biomaterials (Review)

et al. 2009

View full text Add to dashboard Cite

This review focuses on the surface modification of substrates with self-assembled monolayers (SAMs) and polymer brushes to tailor interactions with biological systems and to thereby enhance their performance in bioapplications. Surface modification of biomedical implants promotes improved biocompatibility and enhanced implant integration with the host. While SAMs of alkanethiols on gold substrates successfully prevent nonspecific protein adsorption in vitro and can further be modified to tether ligands to control in vitro cell adhesion, extracellular matrix assembly, and cellular differentiation, this model system suffers from lack of stability in vivo. To overcome this limitation, highly tuned polymer brushes have been used as more robust coatings on a greater variety of biologically relevant substrates, including titanium, the current orthopedic clinical standard. In order to improve implant-bone integration, the authors modified titanium implants with a robust SAM on which surface-initiated atom transfer radical polymerization was performed, yielding oligo(ethylene glycol) methacrylate brushes. These brushes afforded the ability to tether bioactive ligands, which effectively promoted bone cell differentiation in vitro and supported significantly better in vivo functional implant integration.

show abstract

“…These are of interest for applications ranging from chemical sensing [1] to microelectronics [2] and catalysis [3]. Thiols -organic compounds carrying a SH group -are widely used to anchor organic layers to gold surfaces [4], because gold is catalytically sufficiently active to replace relatively weak S-H bonds with Au-S bonds, yet is too inert to attack C-C and C-H bonds present in the organic layer.…”

Section: Introductionmentioning

confidence: 99%

High temperature stability of n-decanethiol by adsorption on nickel powders used as reforming catalysts in solid oxide fuel cells (SOFC)

Hassani¹,

Abatzoglou²,

Rakass³

et al. 2007

WIT Transactions on Ecology and the Environment, Vol 105

View full text Add to dashboard Cite

Solid Oxide Fuel Cells (SOFC) are among the most promising electricity producing technologies. Their successful implementation and versatility depends upon a number of still not fully solved technological issues; namely, the possibility of using both fossil and renewable energy vectors is one of the most significant. Such energy vectors, constituting a crucial SOFC feedstock, are the natural gas, the biogas and all forms of fossil and renewable liquid fuels like diesel, biodiesel, "green" diesel. These fuels require a conversion step because SOFC can use only H 2 and CO. This conversion step is achieved through catalytic reforming and/or partial oxidation. The most successful catalysts are ceramic-supported bimetallic composites. The presence of sulphur in the fuels is detrimental to the catalysts and constitutes one of the basic hurdles in scaling-up and adopting commercially these conversion technologies.In this paper, the authors, based on their previous work on the role of sulphur on micronic Ni powders used as CH 4 reforming catalysts, study the behaviour of medium size thiols adsorbed at the surface of the Ni powders and treated thermally in a differential reactor set-up. The Diffuse Reflectance Infra-red Fourier Transform Spectroscopy (DRIFTS) analyses before and after adsorption and thermal treatments have shown that these Ni surfaces stabilize the adsorbed hydrocarbon chains and alter their catalytic properties during reforming. These results are quite surprising and open the field to a positive synergy between surface chemists and engineers in an effort to better control the efficiency and improve the tolerance to sulphur of these reforming catalysts.

show abstract

Patterned polymer growth on silicon surfaces using microcontact printing and surface-initiated polymerization

Cited by 159 publications

References 23 publications

In Pursuit of Zero: Polymer Brushes that Resist the Adsorption of Proteins

In Pursuit of Zero: Polymer Brushes that Resist the Adsorption of Proteins

Polymer brushes and self-assembled monolayers: Versatile platforms to control cell adhesion to biomaterials (Review)

High temperature stability of n-decanethiol by adsorption on nickel powders used as reforming catalysts in solid oxide fuel cells (SOFC)

Contact Info

Product

Resources

About