Pattern of uveitis in children.

Abstract

THE comparatively few accounts of uveitis in children all agree that it is uncommon (Table I). This report concerns 150 cases of uveitis starting before the age of 16 years. Most of the children were below this age when first seen; although 5 were aged between 16 and 20 and 3 were over 20, there was good documentary evidence that the uveitis had started before the age of 16. The 150 cases represent 5 per cent. of the total of 2,890 referred to the Uveitis Clinic of the Institute of Ophthalmology in the period from 1956 to 1964. The proportion of children under 15 years of age in the population of England and Wales in 1951 was over 20 per cent., so that there are fewer cases of uveitis in children than would be expected from the age structure of the population. It is interesting that Davis (1953) found a similar proportion of cases of uveitis in children-21 out of a total of 400-and Kimura, Hogan, and Thygeson (1954) 5 8 per cent. of 810 cases of uveitis. TABLE I INCIDENCE OF UVEITIS IN CHILDREN Author~~~Total in No. of Age Group Percentage Author Series Children (years) of Total Blegvad (1941) 896 20 Under 15 2-2 Guyton and Woods (1941) 562 7 Under 10 1*3 59 10-19 8-8 Marchesani (1949) 451 17 Under 15 3-7 Davis (1953) 400 21 Under 16 5 0 Kimura, Hogan, and Thygeson (1954) 810 47 Under 16 5*8 Bennett (1955) 332 7 Under 15 2-1 Perkins (1961) 1,718 40 Under 1 1 2-3 169 11-20 9-8 The cases inevitably represent a selected group, as only those which were more severe and chronic are likely to have been referred for investigation. The methods of investigation used in the clinic have been described previously (Perkins, 1961).

Pattern of uveitis in a referral centre in Tunisia, North Africa

“…9,12,14,15 The rate of children in our uveitis population (10%) was slightly higher than most estimates from previous studies. [30][31][32] Data from referral centres revealed that anterior uveitis was the most common form of uveitis (27.8-63%), followed by posterior (9.3-38%) or panuveitis (7-38%), and intermediate uveitis (4-17%). 33 Chronic uveitis were more common than acute uveitis, and nongranulomatous uveitis occurred more frequently than did granulomatous uveitis.…”

Uveitis in children: Population‐based study in Finland

“…In earlier studies from tertiary referral centers PU cases have been reported to comprise 13.8% to 62% of all cases (Kimura et al 1954;Perkins 1966;Kazdan et al 1967;Makley et al 1969;Pivetti-Pezzi 1996;Tugal-Tutkun et al 1996). The relative frequencies with which various forms of uveitis are seen in a tertiary referral center do not necessarily reflect the true distribution with which they are seen in the general population (McCannel et al 1996).…”

“…The preponderance of girls in children with CAU has been shown in all reported series (Perkins 1966;Key & Kimura 1975;Ohno et al 1977;Kanski & Shun Shin 1984). It is accepted that the type of CAU typically associated with JRA can occur in the absence of joint involvement, particularly in girls (Perkins 1966;Ohno et al 1977;Kanski 1981). In our material, however, the prevalence rate for idiopathic CAU did not show significant difference between girls and boys.…”

“…As in adults, uveitis in children may form one of the specific uveitis syndromes which is not associated with any underlying systemic disorder, or it may be associated with a specific systemic disease (Kanski 1990). The most common systemic association is juvenile rheumatoid arthritis (Perkins 1966;Ohno et al 1977;Kanski & Shun Shin 1984;Kanski 1988Kanski , 1990Pivetti Pezzi 1996;Tugal-Tutkun et al 1996;Akduman et al 1997;Dana et al 1997). Other systemic disease associations reported in children with uveitis include tuberculosis (Perkins 1966), syphilis (Kazdan et al 1967), sarcoidosis (Perkins 1966;Hoover et al 1986;Sahn et al 1990), and the HLA-B27 related juvenile spondyloarthropathies (Ostler et al 1971;Perkins 1966;Southwood et al 1989).…”

“…U veitis is less common in children than in adults, and about 2.1 to 9.7% of all cases of uveitis occur in children under the age of 16 years (Kimura et al 1954;Bennett 1955;Perkins 1966;Giles. 1988).…”