Pattern of muco-cutaneous manifestations in HIV infected children at tertiary care hospital, north Karnataka, India

Abstract

Background: Mucocutaneous diseases are more common children with HIV infection than normal population. These develop a wide variety of infectious and inflammatory diseases of the skin. In some cases, disorders of the skin or mucous membrane may provide an early clue to the presence of HIV infection. Objective: To determine the prevalence and pattern of mucocutaneous manifestation in HIV infected children. Methods: All serologically positive children admitted in paediatric ward of S. Nijalingappa Medical College, Bagalkot, between the age group of 18 months to 14 years were studied from October 2010 to March 2012 (18 months period). Clinical information was collected using standard questionnaire. Results: 85 children who fulfilled inclusion criteria were enrolled in the study. 57 children had mucocutaneous manifestation and most of them were aged more than 5 years. The most prevalent mucocutaneous disorders were infectious dermatosis. Most of them were seen with WHO stage III and IV, and with moderate and severe immunosuppresion. Two or more mucocutaneous disorders were found in moderate and severe immunosuppresion. Conclusions: The prevalence of mucocutaneous disorders is high in HIV infected children with varied pattern. Advanced immunosuppresion is highly associated with a wide spectrum of mucocutaneous disorders.

Patterns of common skin infections among children living with HIV/AIDS in Hawassa City, Ethiopia: a cross sectional study

“…This study showed that 72% of children had at least one type of skin disorders. Similar to our study, high prevalence of skin and mucocutaneous infections has been reported in Addis Ababa, 72.6% and 79% [6, 7], in Cameroon (68.8%) [10], in Nigeria (72%) [11], and India (67.06%) [9]. Nevertheless, the finding lower than studies from Tanzania (85%) [12], Zimbabwe 88% [13] and, India 93.7% [14] and (88.3%) [15] and higher than a study conducted in Guinea (54.62%) [16].…”

“…The aim of this study was to assess the pattern of skin problems among children living with HIV/AIDS attending in Hawassa University comprehensive specialized hospital, Hawassa, Ethiopia. Thus, skin and mucocutaneous infections can be the early indication of HIV-associated compromised immune system [2, 9]. Therefore, identification of these HIV-related skin problems may possibly lead to early diagnosis of HIV infection and endowing with timely initiation of appropri-ate ART [2].…”