Pattern of Intermediate Uveitis in an Egyptian Cohort

Latif, Eiman Abd El; Abdelhalim, Ahmed Shawkat; Montasser, Ahmed Samir; Said, Mohamed Hassan; Ahmed, Mahmoud; Galal, Marwa Abdel Kader Fouly; Ibrahim, Walid; Elaziz, Mohamed Samy Abd; Abuelkheir, Amr Fathi; Elbarbary, Hossameldeen; Elsayed, Ayman M Abdelrahman; Lotfy, Ayman; Elmorsy, Osama A.; Gab-Alla, Amr A; Hatata, Ragai Magdy; AbouSamra, Amir; Farouk, Mahmoud; Elbakary, Molham A; Awara, Amr M; Amer, Ibrahim M.; Elzawahry, Walid Mohamed; Kandil, Hazem W; Barrada, Omar A.; Elessawy, Kareem B; Zayed, Mohamed A; Hennawi, Hazem El; Tawfik, Mohamed A

doi:10.1080/09273948.2019.1668429

Cited by 6 publications

(1 citation statement)

References 45 publications

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“…(2019), Japan [ 50 ] 8 Eight TINU Pt within a cohort of 156 Pt with noninfectious uveitis NA NA Topical steroid monotherapy in 6/8 Pt, other 2 Pt received long-term steroids NA Betamethasone eye drops, topical triamcinolone acetonide, and long-term, systemic corticosteroids were the major therapeutic strategies used for uveitis relapse or exacerbation Abd et al . (2020), Egypt [ 51 ] 8 Eight TINU Pt within a cohort of 781 Pt with intermediate uveitis NA NA NA NA 40% of patients with intermediate uveitis had identifiable a systemic disease Clave et al . (2019), France [ 25 ] 7 Five male and two female Pt, aged 10.1–14.5 years, all with bilateral uveitis and renal involvement All Pt with elevated serum creatinine and lower GFR, other laboratory data NA NA Full-dose steroid treatment was maintained for 1 month in all Pt, followed by gradual tapering.…”

Section: Discussionmentioning

confidence: 99%

Tubulointerstitial nephritis and uveitis syndrome in an adolescent female: a case report

2021

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Background Tubulointerstitial nephritis with uveitis syndrome is a rare disease affecting mainly children and young women. Tubulointerstitial nephritis with uveitis is a diagnosis of exclusion, requiring a high degree of clinical suspicion. Studies report recent infections or certain drugs as precipitating factors of a lymphocytic oculorenal immune response. The prognosis is usually favorable with topical and systemic corticosteroid therapy. Case presentation We report a literature review and the case of a 14-year-old white girl, who presented to the ophthalmology department with features of one-sided uveitis. Upon transfer of patient to nephrological care, diagnostic work-up revealed renal involvement. Renal biopsy showed a mixed-cell and granulomatous tubulointerstitial nephritis with some noncaseating granulomas, leading to a diagnosis of tubulointerstitial nephritis with uveitis syndrome. With topical ocular and systemic corticosteroid therapy, the patients’ condition improved over several weeks. Conclusions Our case highlights the importance of early recognition and treatment of this syndrome, where cross-specialty care typically leads to a favorable outcome.

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