Pattern of hepatitis virus infection among pregnant women and their newborns at the Women's Health Center of Assiut University, Upper Egypt

Zahran, Kamal M.; Badary, Mohamad S.; Agban, Michael N.; Aziz, Nafesa H.R. Abdel

doi:10.1016/j.ijgo.2010.06.013

Cited by 49 publications

(49 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, there is a great controversy in studies conducted in different Arab countries concerning the impact of blood transfusion on the status of HBV infection. Studies from Egypt have reported that HBV infection was found to be associated with blood transfusion among pregnant women along with the finding that it is also associated with HBV infection in patients with chronic hematological disorders requiring frequent blood transfusions [29,95]. Several other studies have reported higher prevalence among those dependent on blood and blood products, especially when compared with reports of a decline in seroprevalence [96][97][98][99][100][101].…”

Section: Factors Associated With Transmission Of Hbv Among Pregnant Wmentioning

confidence: 98%

“…HBV is extensively studied in Egypt, where appreciable efforts have been made in this setting [28]. Although there is a high prevalence of HBV (6.7%) among the general population in Egypt [28], the prevalence among pregnant women is only 4% [29]. The prevalence of HBV among pregnant Sudanese women (5.6%) is comparable to the prevalence in Egyptian women [30].…”

Section: Hbv Among Pregnant Women In the Arabian Nile River Regionmentioning

confidence: 99%

“…Risk of HCV infection from a single unit of transfused blood has declined to less than one per million transfused units [102]. However, the risk of HCV transmission through blood still exists in some developing countries because of failure to adequately screen donors due to financial constraints [29,103]. However, most studies have found that blood transfusion is no longer a risk factor for HCV in pregnancy [50,104], and the same is generally true in Arab countries [24], although some Arab countries have found it to be a risk factor [50].…”

Section: Factors Associated With Transmission Of Hcv Among Pregnant Wmentioning

confidence: 99%

See 2 more Smart Citations

Hepatitis B and C virus infections among pregnant women in Arab and African countries

Gasim

Murad

Adam

2013

J Infect Dev Ctries

View full text Add to dashboard Cite

Introduction: The epidemiology of viral hepatitis during pregnancy is of paramount importance for health planners and program managers. Data on viral hepatitis during pregnancy are not readily available in many African and Arab countries. Both regions have their own unique geography, and comprise over 59 states with crossover and interaction of different cultures. Methodology: A systematic electronic search of the published literature was conducted and data on epidemiology and risk factors of maternal hepatitis B virus (HBV) infection and hepatitis C (HCV) infection in Arab and African countries were extracted from relevant studies. Results: The serology of hepatitis viruses varies greatly among these countries, with different viral genotype patterns. Such a variation in prevalence could be explained by the different risk factors involved. Sexual contact, perinatal infection, blood and its derivatives, hemodialysis, intravenous and percutaneous drug use, and occupational, habitual, and social behavior have been identified as risk factors for hepatitis transmission in various settings in these countries. Conclusions: Infection from hepatitis B and C viruses imposes major socioeconomic and even political burdens on such young and dynamic societies. Thus strategies and clear policies of intervention are required to combat the consequences of hepatitis B and C at both the regional and national levels.

show abstract

Section: Factors Associated With Transmission Of Hbv Among Pregnant Wmentioning

confidence: 98%

Section: Hbv Among Pregnant Women In the Arabian Nile River Regionmentioning

confidence: 99%

Section: Factors Associated With Transmission Of Hcv Among Pregnant Wmentioning

confidence: 99%

See 1 more Smart Citation

Hepatitis B and C virus infections among pregnant women in Arab and African countries

Gasim

Murad

Adam

2013

J Infect Dev Ctries

View full text Add to dashboard Cite

show abstract

“…Although much recent data are available on the epidemiology of HBV and HCV among pregnant women in different countries [12-16], few published data are available from Yemen [5]. Such data are fundamental for health planners and care givers for evidence-based intervention.…”

Section: Introductionmentioning

confidence: 99%

Epidemiology of hepatitis B and hepatitis C virus infections in pregnant women in Sana’a, Yemen

Murad¹,

Babiker

Gasim

et al. 2013

BMC Pregnancy Childbirth

View full text Add to dashboard Cite

BackgroundScreening for Hepatitis B and C during pregnancy may help to decide on appropriate antiviral therapy and the institution of steps to minimize vertical transmission to the newborn infants.MethodsA cross-sectional study was conducted during November–December 2011 to investigate the seroprevalence and associated risk factors for markers of HBV (hepatitis B surface antigen; HBsAg) and anti-HCV antibody among pregnant women at the Al-Thawra hospital in Sana’a, Yemen. Structured questionnaires were used to obtain sociodemographic obstetrics and medical data and sera were tested for HBsAg and anti-HCV.ResultsOf the 400 pregnant women enrolled in the study, HBsAg and anti-HCV were detected in 43 (10.8%; 95% CI: 8.0–14.0%) and 34 (8.5%, 95% CI: 6.0–11.5%) women, respectively. None of the women were co-infected with HBV and HCV. Multivariate analysis showed that circumcision was significantly associated with HBsAg seropositivity (OR = 3.3, 95% CI: 1.1–10.2; p = 0.03), low parity (primigravidae and secundigravidae) and education below secondary level were significantly associated with anti- HCV seropositivity (OR = 3.3, 95% CI: 1.1–10.2; p = 0.03). No other sociodemographic or clinical characteristics (age, residence, history of home delivery, miscarriage, dental manipulation, surgery, and blood transfusion) were significantly associated with HBsAg or anti-HCV seropositivity.ConclusionThe results of this study suggest that HBsAg and anti-HCV have high prevalence among pregnant women.

show abstract

“…18,116 Maternal and neonatal outcomes, including gestational diabetes, preterm delivery, and low birth weights, have been reported. [117][118][119][120] In addition, vertical transmission plays a major role in pediatric hepatitis C 121 ; the prevalence of mother-tochild transmission from HCV-infected women without HIV infection is an estimated 2-8%, 18,115,122,123 and 2-3 times higher in mothers co-infected with HIV. [124][125][126][127] There is currently no vaccine for hepatitis C, 15,128 and immune globulin is not effective in preventing pre-or postexposure HCV infection.…”

Section: -112mentioning

confidence: 99%

Viral hepatitis vaccination during pregnancy

Zhao

Jin

Zhang

et al. 2016

Human Vaccines & Immunotherapeutics

View full text Add to dashboard Cite

Viral hepatitis is a serious global public health problem. It is also a common cause of jaundice and gestational complications in pregnant women. Moreover, infected mothers can transmit the virus to their fetus or neonate, which may increase disease burden and decrease quality of life. To date, commercial vaccines have been developed for hepatitis A, B, and E and are available to the general population. The Advisory Committee on Immunization Practices currently accepts emergency vaccination against hepatitis A and B during pregnancy due to benefits that overweight the potential risks. While there are limited data from trials with limited numbers of samples that suggest the efficacy or safety of hepatitis B and E vaccines in pregnant women, additional data are necessary to provide evidence of vaccination during pregnancy.

show abstract

Pattern of hepatitis virus infection among pregnant women and their newborns at the Women's Health Center of Assiut University, Upper Egypt

Abstract: Infection with HBV and/or HCV is highly prevalent among pregnant women in Upper Egypt. The rate of vertical transmission was also high. Administering hepatitis B vaccine and immunoglobulin resulted in a 92% reduction in carrier status among newborns.

Cited by 49 publications

References 17 publications

Hepatitis B and C virus infections among pregnant women in Arab and African countries

Hepatitis B and C virus infections among pregnant women in Arab and African countries

Epidemiology of hepatitis B and hepatitis C virus infections in pregnant women in Sana’a, Yemen

Viral hepatitis vaccination during pregnancy

Contact Info

Product

Resources

About