Pattern of bacterial isolates in the middle ear discharge of patients with chronic suppurative otitis media in a tertiary hospital in North central Nigeria

Afolabi, OA; Salaudeen, A.G.; Ologe, Foluwasayo E.; Nwabuisi, C; Nwawolo, C C

doi:10.4314/ahs.v12i3.18

Cited by 60 publications

(74 citation statements)

References 21 publications

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“…7,14 Chronic suppurative otitis media can cause many complications, including mastoiditis and meningitis, if not treated properly. Therefore, identification of the causative organisms is essential for proper management of CSOM.…”

Section: Discussionmentioning

confidence: 99%

A study of bacterial pathogens and antibiotic susceptibility patterns in chronic suppurative otitis media

et al. 2017

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Objective: To assess the frequency of bacterial agents in chronic suppurative otitis media and the antibiotic susceptibility patterns of isolates among patients.Methods: A total of 185 patients clinically diagnosed with chronic suppurative otitis media were interviewed and middle-ear effusion samples were collected using sterile swabs. All bacterial isolates were identified by conventional microbiological methods. Antibiotic susceptibility patterns of the isolates were determined by Kirby-Bauer disc diffusion.Results: Staphylococci spp. (64.9 per cent) were the most prevalent bacteria isolated, followed by Klebsiella spp. (12.9 per cent) and Pseudomonas aeruginosa (10.3 per cent). The most effective antibiotic for treatment of bacterial chronic suppurative otitis media was ciprofloxacin. Statistical analysis showed no significant difference in bacterial infestations among chronic suppurative otitis media patients and the antimicrobial susceptibility patterns of the bacterial isolates based on gender and age ( p > 0.05).Conclusion: Our findings highlight the importance of a continuous and periodic evaluation of the bacteriological profile and antibiotic susceptibility patterns in chronic suppurative otitis media patients for efficacious treatment of the infection.

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Section: Discussionmentioning

confidence: 99%

A study of bacterial pathogens and antibiotic susceptibility patterns in chronic suppurative otitis media

et al. 2017

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“…Otitis media which is inflammation of the middle ear cleft has been reported as a common childhood disease (Cripps and Kyd, 2003;Afolabi et al, 2012;Wasihun and Zemene, 2015;Ngo et al, 2016). It is associated with multiple microbial pathogens within the middle ear (Ngo et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

“…It is associated with multiple microbial pathogens within the middle ear (Ngo et al, 2016). It has a high incidence and prevalence in both developed and developing countries (Afolabi et al, 2012). It is classified as acute, chronic or recurrent and can also be suppurative or non-suppurative.…”

Section: Introductionmentioning

confidence: 99%

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Antibiotic susceptibility pattern of bacterial isolates in children with otitis media in Zamfara, North-Western Nigeria

Garba¹,

Mohammed²,

Mohammed³

et al. 2017

Afr. J. Microbiol. Res.

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Otitis media has been reported as a common childhood disease and is associated with multiple microbial pathogens within the middle ear. Though the causative agents of this infection have largely remained the same over the years, current literature reviews show that the antibiotic susceptibility pattern has changed considerably. This study aimed to identify bacterial isolates and determine their antibiotic susceptibility and resistance patterns in children who had otitis media. This is a retrospective analysis of ear swab microscopy, culture and sensitivity (MCS) results of children between the age of 0 and 13 years who presented with clinical episodes of otitis media over a four year period. A total of 53 results were retrieved from the laboratory record book of which 43 were culture positive giving a yield of 84.9%. Males were 33 (62.3%) giving a M:F ratio of 1.7:1 and 71.7% were below the age of 5 years. Majority (68.9%) of the isolates were Gram positive organisms with Staphylococcus aureus being the commonest bacteria isolated (53.3%), followed by Pseudomonas aeruginosa (20.0%) and then Streptococcus pyogenes (13.3%). The isolates were highly susceptible to ciprofloxacin, ofloxacin and gentamicin, while all were found to be resistant to tetracycline, cefixime and levofloxacin. S. aureus, P. aeruginosa and S. pyogenes were the commonest bacterial isolates in the patients. Ciprofloxacin, ofloxacin and gentamicin were the antibiotics with the highest bacterial susceptibility rate. Children with ear discharge were recommended to be investigated and treatment should be based on antimicrobial test to prevent resistance and probably complications.

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“…[7][8][9][10][11][12] Sensitivity rate of P. aeruginosa to ciprofloxacin in our study was 96%. This rate is comparable to various studies mentioned above.…”

Section: Discussionmentioning

confidence: 72%

Prevalence of Pseudomonas aeruginosa in CSOM cases at a tertiary care centre

Maringanti

Archana

2017

Int J Otorhinolaryngol Head Neck Surg

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Background: Chronic suppurative otitis media (CSOM) is an infectious chronic ear disease in India characterised by discharge from ear. This is the commonest infection in children more so in low socio economic group. CSOM is caused by various gram positive and gram negative organisms.Methods: Study group includes CSOM patients coming to ENT Department of Kamineni Institute of Medical Sciences, Narketpally, Telangana, India. Swabs were taken from discharging ears and sent for Gram’s staining, culture and antibiotic sensitivity. The results were analysed and a protocol was devised for effective treatment of Pseudomonas aeruginosa. Results: Total numbers of study group were 180 of. 180 patients, 84 were males and 96 were females. CSOM infection was found to be more common in 11-30 yrs age group. When the ear discharge was sent for culture and sensitivity only 106 patients out of 180, showed culture positivity. Pseudomonas aeruginosa was the most common organism identified. Its prevalence in the present study was 23%. Methicillin Resistant Staphylococcus aureus (MRSA) and Klebsiella sps were the next common isolates, whose prevalence was detected to be 10% and 8% respectively. Pseudomonas is resistant to all routine broad spectrum antibiotics like amoxicillin, ampicillin and amoxycillin - clavulanate and cephalosporins, but sensitive to ciprofloxacin, gentamycin, imipenem, meropenem, piperacillin.Conclusions: CSOM is common among children and young adults. Pseudomonas aeruginosa was the most common isolate (23%) in our study. As Pseudomonas was found to be resistant to routine antibiotics, inadvertent use of routine antibiotics will lead to the development of multidrug resistant strains in the community which are difficult to treat. Specific antibiotic treatment should be started based on the culture and antibiotic sensitivity report of the swab.

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Pattern of bacterial isolates in the middle ear discharge of patients with chronic suppurative otitis media in a tertiary hospital in North central Nigeria

Cited by 60 publications

References 21 publications

A study of bacterial pathogens and antibiotic susceptibility patterns in chronic suppurative otitis media

A study of bacterial pathogens and antibiotic susceptibility patterns in chronic suppurative otitis media

Antibiotic susceptibility pattern of bacterial isolates in children with otitis media in Zamfara, North-Western Nigeria

Prevalence of Pseudomonas aeruginosa in CSOM cases at a tertiary care centre

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