Abstract:Aortic aneurysms in Kenya show abdominal segment and female predominance, occur 10 to 15 years earlier than in white populations, and carry high mortality from rupture. Hypertension was the leading associated risk factor. Ultrasonographic screening and control of blood pressure might be useful preventive measures.
“…Abdominal aortic segment predominance observed in the current study is commensurate with recent findings in Kenya [3]. This suggests that the preponderant involvement of this segment is related to generalized, perhaps intrinsic, factors such as reduced wall thickness and absence of vasa vasora [10].…”
Section: Localizationsupporting
confidence: 90%
“…The early onset of aneurysms suggests that lifestyle modification among youth constitutes useful control measures for aneurysms. Male predominance in this age group is at variance with recent reports from Kenya on all age cohort that aortic aneurysms for example are female predominant [3]. This difference may be due to the widely held view that estrogen protects arteries against aneurysm formation [34].…”
Section: Age and Gender Distributioncontrasting
confidence: 63%
“…A significant proportion of individuals suffer aneurysms before 40 years [1][2][3][4]. In black Africans, aneurysms occur 10-15 years earlier than in Caucasians [3,5,6].…”
Section: Introductionmentioning
confidence: 99%
“…In black Africans, aneurysms occur 10-15 years earlier than in Caucasians [3,5,6]. Because of epidemiological transition [7], and increasing cardiovascular risk factors in young people [8], a rise in aneurysms in this age group is imminent.…”
Background Reports on pattern of aneurysms among young people are scanty. These data are important for informing preventive and management strategies. This retrospective study at Kenyatta National Hospital, Nairobi. Kenya describes the pattern of aneurysms among young black Kenyans. Patients and methods Records of in-patients, aged up to 40 years, with a diagnosis of aneurysm between January 1998 and December 2007 were examined for localization, presentation, investigations, comorbidities, age and gender distribution. Data were analyzed by SPSS version 13.0 for Windows, and presented in tables and bar charts. Results One hundred and fifteen files were analyzed. Most frequent site was abdominal aorta (32.2%). Of these, majority (59.4%) were infrarenal. Other commonly affected arteries included thoracic aorta (11.3%), posterior communicating (7.8%), femoral (8.7%), brachial (8.7%), common carotid (6.1%) and internal thoracic (5.2%). They presented as pulsatile, often painful masses, and with pressure symptoms. Diagnosis was confirmed by ultrasound and angiography. Common comorbidities were hypertension, smoking, Human Immunodeficiency Virus infection, alcohol, trauma, and connective tissue disorders. Mean age was 26.1 years and male: female ratio was 2.7:1. Conclusion Aneurysms are not uncommon in young Kenyans. They occur more commonly in males than females, and affect diverse vascular beds. Associated comorbidities comprise non communicable lifestyle factors, infection, inborn conditions and trauma. Lifestyle modification from early in life and control of infections are recommended.
“…Abdominal aortic segment predominance observed in the current study is commensurate with recent findings in Kenya [3]. This suggests that the preponderant involvement of this segment is related to generalized, perhaps intrinsic, factors such as reduced wall thickness and absence of vasa vasora [10].…”
Section: Localizationsupporting
confidence: 90%
“…The early onset of aneurysms suggests that lifestyle modification among youth constitutes useful control measures for aneurysms. Male predominance in this age group is at variance with recent reports from Kenya on all age cohort that aortic aneurysms for example are female predominant [3]. This difference may be due to the widely held view that estrogen protects arteries against aneurysm formation [34].…”
Section: Age and Gender Distributioncontrasting
confidence: 63%
“…A significant proportion of individuals suffer aneurysms before 40 years [1][2][3][4]. In black Africans, aneurysms occur 10-15 years earlier than in Caucasians [3,5,6].…”
Section: Introductionmentioning
confidence: 99%
“…In black Africans, aneurysms occur 10-15 years earlier than in Caucasians [3,5,6]. Because of epidemiological transition [7], and increasing cardiovascular risk factors in young people [8], a rise in aneurysms in this age group is imminent.…”
Background Reports on pattern of aneurysms among young people are scanty. These data are important for informing preventive and management strategies. This retrospective study at Kenyatta National Hospital, Nairobi. Kenya describes the pattern of aneurysms among young black Kenyans. Patients and methods Records of in-patients, aged up to 40 years, with a diagnosis of aneurysm between January 1998 and December 2007 were examined for localization, presentation, investigations, comorbidities, age and gender distribution. Data were analyzed by SPSS version 13.0 for Windows, and presented in tables and bar charts. Results One hundred and fifteen files were analyzed. Most frequent site was abdominal aorta (32.2%). Of these, majority (59.4%) were infrarenal. Other commonly affected arteries included thoracic aorta (11.3%), posterior communicating (7.8%), femoral (8.7%), brachial (8.7%), common carotid (6.1%) and internal thoracic (5.2%). They presented as pulsatile, often painful masses, and with pressure symptoms. Diagnosis was confirmed by ultrasound and angiography. Common comorbidities were hypertension, smoking, Human Immunodeficiency Virus infection, alcohol, trauma, and connective tissue disorders. Mean age was 26.1 years and male: female ratio was 2.7:1. Conclusion Aneurysms are not uncommon in young Kenyans. They occur more commonly in males than females, and affect diverse vascular beds. Associated comorbidities comprise non communicable lifestyle factors, infection, inborn conditions and trauma. Lifestyle modification from early in life and control of infections are recommended.
“…This was despite the predominant African descent of the population and the prevalence of high blood pressure in the 50- to 64-year age category, which was the leading risk factor associated with aortic aneurysms in this study 17. This apparent inconsistency might be due to methodological factors, such as gender differences in health-related habits, since the Kenyan study was based on hospital records and not on population-based data.…”
The prevalence of abdominal aortic aneurysm (AAA) and its risk factors are well known in Western countries but few data are available from low- and middle-income countries. We are not aware of systematically collected population-based data on AAA in the African region. We evaluated the prevalence of AAA in a population-based cardiovascular survey conducted in the Republic of Seychelles in 2004 (Indian Ocean, African region). Among the 353 participants aged 50 to 64 years and screened with ultrasound, the prevalence of AAA was 0.3% (95% CI: 0–0.9) and the prevalence of ectatic dilatations of the abdominal aorta was 1.5% (95% CI: 0.2–2.8). The prevalence of AAA in the general population seemed lower in Seychelles than in Western countries, despite a high prevalence in Seychelles of risk factors of AAA, such as smoking (in men), high blood pressure and hypercholesterolaemia.
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