The application of machine learning algorithms in studying injury assessment methods based on data analysis has recently provided a new research insight for sports injury prevention. However, the data used in these studies are primarily multi-source and multimodal (i.e., longitudinal repeated-measures data and cross-sectional data), resulting in the models not fully utilising the information in the data to reveal specific injury risk patterns. Therefore, this study proposed an injury risk prediction model based on a multi-modal strategy and machine learning algorithms to handle multi-source data better and predict injury risk. This study retrospectively analysed the routine monitoring data of sixteen young female basketball players. These data included training load, perceived well-being status, physiological response, physical performance and lower extremity non-contact injury registration. This study partitions the original dataset based on the frequency of data collection. Extreme gradient boosting (XGBoost) was used to construct unimodal submodels to obtain decision scores for each category of indicators. Ultimately, the decision scores from each submodel were fused using the random forest (RF) to generate a lower extremity non-contact injury risk prediction model at the decision-level. The 10-fold cross-validation results showed that the fusion model was effective in classifying non-injured (mean Precision: 0.9932, mean Recall: 0.9976, mean F2-score: 0.9967), minimal lower extremity noncontact injuries risk (mean Precision: 0.9317, mean Recall: 0.9167, mean F2score: 0.9171), and mild lower extremity non-contact injuries risk (mean Precision: 0.9000, mean Recall: 0.9000, mean F2-score: 0.9000). The model performed significantly more optimal than the submodel. Comparing the fusion model proposed with a traditional data integration scheme, the average Precision and Recall improved by 8.2 and 20.3%, respectively. The decision curves analysis showed that the proposed fusion model provided a higher net benefit to athletes with potential lower extremity non-contact injury risk. The validity, feasibility and practicality of the proposed model have been