Pattern and burden of opioid‐related hospitalizations in the USA from 2016 to 2018

Abstract

The current opioid crisis in the USA is a formidable challenge for the healthcare system, and the general population. Our objective is to characterize the burden of opioid-related disorders in an inpatient setting in the USA for the years 2016, 2017 and 2018 using the National Inpatient Sample (NIS). Methods: A cross-sectional analysis of the NIS was performed to identify and analyse hospitalizations with an opioid-related diagnosis in 2016, 2017 and 2018. Descriptive statistics and regression models were utilized to define the demographics of the population of interest and measure the outcomes. Results: We identified 962 900 discharges with opioid-related diagnosis in 2016, 982 710 in 2017 and 942 110 in 2018. The majority were age <60 years, were found in residents of low-income zip codes and covered by Medicaid.

The burden of mental health-related mortality in the Baltic States in 2007-2018

“…Current literature stresses the threat of growing importance of drug-related epidemics leading to notable mortality increases in some countries such as the US and Canada [ 39 – 41 ]. Although, with an exception of the UK, there is no significant evidence about similar scale crisis in Europe, there are some warning signs, including transient peaks in opioid-related consumption, poisoning, and mortality in the three Baltic countries [ 42 ].…”

Exemplar Hospital initiation trial to Enhance Treatment Engagement (EXHIT ENTRE): protocol for CTN-0098B a randomized implementation study to support hospitals in caring for patients with opioid use disorder

“…The primary, secondary, and most exploratory outcome effectiveness measures will be derived from state Medicaid claims data (Table 1 ). Medicaid claims were selected because Medicaid is the most common payer for opioid-related hospitalizations and for outpatient MOUD [ 5 , 43 , 44 ]. A distributed research network approach using a common data model will allow for standardized analyses and comparisons across states without the need for data-sharing agreements between states [ 45 ].…”

Identification of factors associated with opioid-related and hepatitis C virus-related hospitalisations at the ZIP code area level in the USA: an ecological and modelling study

“…Recent escalation in the number of opioid-related hospitalisations and deaths has raised concerns about the prevalence of opioid misuse and its effect on public health in the USA. 1 , 2 Annual deaths caused by overdose have increased by more than 50% since January, 2020, surpassing 110 000 in 2023. 3 Additionally, opioid use through injection drug practices is creating a surge in infectious disease prevalence, adding to the public health crisis.…”