Patrón de sensibilización por contacto a parafenilendiamina y su detección en tintes capilares

Contact Dermatitis Due to Hair Care Products: A Comprehensive Review

“…In cases of ACD affecting the scalp, dyes emerge as the most frequently cited culprits, followed by shampoos and conditioners. Within dyes, PPD stands out as the predominant allergen [15][16][17] . PPD, an oxidative dye found in numerous coloring products 18 , exhibits its highest concentration in dark shades, although it is also present in brighter colors.…”

“…Although most documented cases of allergic contact dermatitis (ACD) linked to hair dyes are linked to PPD-phenylenediamine (PPD), there are few other compounds in hair dyes recognized for their strong sensitizing potential. PPD is used as a component in both permanent and semipermanent hair dyes 15,38 . While it serves as a coloring agent in various cosmetic products, the main source of sensitization to PPD is exposure through the use of hair dyes.…”

“…Since various hair dyes fall into categories like permanent, semi-permanent, and temporary, positive patch test results for different dyes may be misconstrued as initial sensitization. However, it is essential to also contemplate the possibility of cross-sensitization to distinct azo dyes and para-amino compounds, as reported in some instances, or concurrent contact allergy 15,30,57 . Paradoxically, several studies suggest that the occurrence of allergic reactions to PPD appears to have decreased in recent years, despite the worldwide increase in hair dye use.…”

“…The Cosmetic Ingredient Expert Panel asserts the safety of 2-amino-4hydroxyethylaminoanisole and its sulfate derivative, utilized as coupling agents in oxidative hair dyes, but cautions against their use in other cosmetic products due to the potential formation of Nnitroso compounds. Periodically, allergic contact dermatitis cases have been documented for certain components of temporary dyes, including quinine 15,30,57 .…”

Exposición química y síntomas dérmicos y respiratorios en estilistas del sector informal de Palmira 2020

“…Los estilistas se exponen a agentes químicos tóxicos como la parafenilendiamina, persulfatos de amonio, persulfatos de potasio, hidróxido de amonio y formaldehidos presente en los productos cosméticos utilizados (4,5) . Estas sustancias pueden causar efectos irritantes como la tos, la flema y la disnea (6) y enfermedades como asma ocupacional, bronquitis crónica (7,8) , y cáncer (9)(10)(11)(12) .…”