Patients with ovarian carcinoma upstaged to Stage III after systematic lymphadenctomy have similar survival to Stage I/II patients and superior survival to other Stage III patients

Clear cell carcinoma of the ovary: a retrospective multicentre experience of 254 patients with complete surgical staging

“…Survival rates with node-positive disease were significantly lower in clinical stage I and II disease Sakuragi et al, 2000;Negishi et al, 2004). In contrast, another report showed that the prognoses for clinical stage I/II patients with or without lymph node metastasis were similar (Onda et al, 1998). In pT1 CCC patients of the present study, lymph node status was identified as a strong prognostic factor and it is essential to accurately evaluate the lymph node status through complete surgical staging procedures.…”

Should we modify the current FIGO staging system for stage IIIC ovarian cancer?

“…In other words, Stage III disease based only on lymph node positivity had fairly good survival. 8 Baek et al 9 reported almost the same results in this issue.…”

Stage IIIC epithelial ovarian cancer classified solely by lymph node metastasis has a more favorable prognosis than other types of stage IIIC epithelial ovarian cancer

“…Some previous studies suggested that the prognoses of stage IIIC patients who are upstaged based on lymph node positivity are as poor as those of patients with stage IIIC based on intraperitoneal tumor spread. 7,23,24 [25][26][27] However, the better survival of patients upstaged to stage IIIC by positive lymph nodes compared to patients with other stage IIIC could simply reflect the prognostic impact of small versus large tumor size. 28 Therefore, a comparison between stage IIIC solely by lymph node metastasis and stage IIIA/IIIB patients would be more appropriate and provide evidence about possible differences in the biological and clinical behavior of lymph node versus peritoneal metastasis.…”