Patients With Diabetes Without Significant Angiographic Coronary Artery Disease Have the Same Risk of Myocardial Infarction as Patients Without Diabetes in a Real-World Population Receiving Appropriate Prophylactic Treatment

Abstract

In a real-world population, patients with diabetes with high rates of statin and aspirin treatment had the same risk of cardiovascular events as patients without diabetes in the absence of angiographically significant CAD.

Mortality risk remains higher in individuals with type 1 diabetes: A population‐based cohort study (the Ayrshire diabetes follow‐up cohort [ADOC])

“…The lack of interaction between hypertension and IHD in type 1 diabetes suggests that the increased risk of mortality in type 1 diabetes is explained by the increased risk of developing these complications rather than an inherent risk associated with diabetes. Cardiovascular disease remains the single largest cause of death in patients with type 1 diabetes . As a result, individuals with diabetes, some without significant IHD, are more likely than their non‐diabetic counterparts to undergo statin therapy, anti‐hypertensive medication, particularly ACE inhibitors, and possibly aspirin therapy…”

“…Cardiovascular disease remains the single largest cause of death in patients with type 1 diabetes. 17,18 As a result, individuals with diabetes, some without significant IHD, are more likely than their non-diabetic counterparts to undergo statin therapy, anti-hypertensive medication, particularly ACE inhibitors, and possibly aspirin therapy. 8,19 Numerous studies have demonstrated that intensive glycaemic control is associated with better outcomes.…”

Primary versus secondary cardiorenal prevention in type 2 diabetes: Which newer anti‐hyperglycaemic drug matters?

“…However, moderate‐intensity statin therapy is recommended for T2D patients above 40 years of age, without considering the occurrence of previous ischaemic events . Within this context, it has been shown that Danish T2D patients without angiographically significant CHD have the same risk of future cardiovascular events as patients without diabetes, if treated with appropriate doses of statin and aspirin …”

“…6 Within this context, it has been shown that Danish T2D patients without angiographically significant CHD have the same risk of future cardiovascular events as patients without diabetes, if treated with appropriate doses of statin and aspirin. 10…”

Reactive Oxygen Species Modulator-1 (ROMO-1) Polymorphism Rs6060566 and The Risk of Myocardial Infarction in Slovenian Subjects With Type 2 Diabetes Mellitus

“…On the other hand, the current study shows that MI is less frequent in subjects with disease-free coronary arteries. Thus, in the absence of angiographically signi cant CAD, patients with diabetes treated with contemporary prophylactic therapy have the same risk of cardiovascular events as patients without diabetes [25]. Therefore, optimal medical therapy and appropriate selection of myocardial revascularization strategy is critical for patients with DM [26].…”