2020
DOI: 10.1055/s-0040-1713435
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Patients with Congenital Bleeding Disorders Appear to be Less Severely Affected by SARS-CoV-2: Is Inherited Hypocoagulability Overcoming Acquired Hypercoagulability of Coronavirus Disease 2019 (COVID-19)?

Abstract: Letter to the Editor 853 This document was downloaded for personal use only. Unauthorized distribution is strictly prohibited.

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Cited by 27 publications
(54 citation statements)
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“…The majority of individuals infected with SARS-CoV-2 are generally asymptomatic, although the most common symptoms of COVID-19 include dry cough, fever, dyspnea, chest pain, headache, and muscle ache 11 , 12 . The issue of hypercoagulability-related thrombotic vascular events in those infected with SARS-CoV-2 is emerging 13 , 14 . Evidence suggests that COVID-19 patients may experience increased rates of thromboembolism, as high as 15%–26% 15 .…”
Section: Introductionmentioning
confidence: 99%
“…The majority of individuals infected with SARS-CoV-2 are generally asymptomatic, although the most common symptoms of COVID-19 include dry cough, fever, dyspnea, chest pain, headache, and muscle ache 11 , 12 . The issue of hypercoagulability-related thrombotic vascular events in those infected with SARS-CoV-2 is emerging 13 , 14 . Evidence suggests that COVID-19 patients may experience increased rates of thromboembolism, as high as 15%–26% 15 .…”
Section: Introductionmentioning
confidence: 99%
“…Clinically diagnosis of COVID‐19 may be difficult since the clinical manifestations of COVID‐19 are very similar to that of various viral infections 6 . In addition, studies have reported laboratory features of COVID‐19 patients 7 . However, unfortunately, these studies are limited to one or few blood indicators.…”
Section: Introductionmentioning
confidence: 99%
“…Hypercoagulability is a common feature of SARS-CoV-2 infection, but the impact of the infection on CBD patients is still unknown. In the literature, the possibility of thromboembolic disorders in this group of patients, a thrombotic episode in a patient with mild VWF disease [ 19 ] and the possibility of bleeding associated with SARS-CoV-2 infection [ 20 ] have all been reported. All the while there is a discussion about a possible association between complications and the level of factor VWF [ 21 , 22 ].…”
Section: Resultsmentioning
confidence: 99%
“…The impact of COVID-19 on the health of patients with congenital bleeding disorders (CBD) is still under discussion. The literature suggests the possibility of thromboembolic disorders, also in patients with CBD [ 19 ]. There are known cases of bleeding related to COVID-19 infection [ 20 ] and also the influence of VWF factor level on the risk of complications is discussed [ 21 , 22 ].…”
Section: Introductionmentioning
confidence: 99%