2016
DOI: 10.1136/postgradmedj-2015-133756
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Patients’ perceptions and views of surgery and radioiodine ablation in the definitive management of Graves’ disease

Abstract: Background Patients’ perceptions and preferences influence the choice of radioiodine ablation (RIA) or surgery in the definitive management of Graves’ disease. This study aimed to evaluate their concerns, experiences and satisfaction following definitive treatment. Methods A postal survey of patients who had treatment with surgery or RIA between January 2011 and June 2013 for Graves’ disease was conducted. … Show more

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Cited by 10 publications
(8 citation statements)
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“…The mean age of the study population was 47 ± 11.94 years, ranging from 19 to 87 years, and the majority of the subjects were Malay (92%). The large variation in age was most probably due to the delayed decision to undergo RAI therapy due to safety concerns regarding the side effects of RAI such as hypothyroidism, scarring and worsening ophthalmopathy 16 . Those who were of reproductive age were concerned about the effects of RAI therapy on their reproductive system i.e., chances of pregnancy and how it would affect breastfeeding.…”
Section: Discussionmentioning
confidence: 99%
“…The mean age of the study population was 47 ± 11.94 years, ranging from 19 to 87 years, and the majority of the subjects were Malay (92%). The large variation in age was most probably due to the delayed decision to undergo RAI therapy due to safety concerns regarding the side effects of RAI such as hypothyroidism, scarring and worsening ophthalmopathy 16 . Those who were of reproductive age were concerned about the effects of RAI therapy on their reproductive system i.e., chances of pregnancy and how it would affect breastfeeding.…”
Section: Discussionmentioning
confidence: 99%
“…Offering patients 3 treatment options, namely ATD, RAI or surgery, necessitates a discussion of the relative merits of each, encompassing both clinical and social factors as well as research evidence. In addition, existing patient preferences and biases will influence how their choice is made . In the absence of clear consensus as to the efficacy of the treatment options, and limited understanding of the factors that influence patients’ choices, investigating patients’ views of how they made their choices and how satisfied they are with the outcome and the resulting QoL is important.…”
Section: Introductionmentioning
confidence: 99%
“…Surgery is the treatment of choice in those with compressive symptoms attributable to goiter, large goiters, presence/suspicion of co-existing malignancy, GD with non-malignant nodule with no/reduced uptake of RAI which is large in size, co-existing parathyroid pathology. Those lactating, pregnant or desirous of pregnancy within next 6 months and presence of significant active ophthalmopathy are advised surgery [5,[18][19][20]. Pediatric patients failing ATD are more likely to undergo thyroidectomy compared to RAI [21].…”
Section: Indications For Surgerymentioning
confidence: 99%
“…More over surgery avoids the long-term systemic side effects of ATD and radiation exposure of RAI. Though a matter of debate, patients having chosen surgery as a definitive treatment are likely to be more satisfied compared to RAI [5,28]. Patients preference should always be taken into consideration.…”
Section: Advantages Of Surgerymentioning
confidence: 99%
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