Patients have very limited knowledge of their contrast allergies

Ruff, Cullen; Banayan, Elliot; Overdeck, Daniel

doi:10.1016/j.clinimag.2021.07.021

Cited by 5 publications

(2 citation statements)

References 17 publications

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“…Ruff C et al found that in a cohort of 307 patients who reported a history of contrast allergy, 98.4% of participants were unable to name which contrast agent or what type of contrast caused their reaction [ 62 ]. Moreover, only about 40% of participants knew the name of the facility where they had the reaction or what city they were in at the time, making it difficult for a provider to request the appropriate health records to determine which contrast to avoid [ 62 ]. Educating patients about their reactions so that they can inform medical professionals about their histories during future scans could help prevent repeat reactions.…”

Section: Contrast Hypersensitivity Preventionmentioning

confidence: 99%

Contrast allergies for neurological imaging: When to proceed

Fusco

Pucci

Pierre

et al. 2022

ALLERGY

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<abstract> <p>Contrast-enhanced neuroimaging is often necessary for the diagnosis and care of patients with diseases of the central nervous system. Although contrast is generally well tolerated and allergy to contrast is rare, allergic reactions can be severe and life threatening. Therefore, physicians should take care to prevent severe contrast allergy. In this review, we will discuss contrast allergy as well as potential strategies to reduce the risk of severe reactions in patients who require neuroimaging techniques with contrast. First, we discuss the clinical presentation and pathogenesis of contrast allergy and the risk factors associated with reactions. We then review methods to reduce the risk of future contrast reactions through improved patient education and documentation strategies, use of alternate imaging modalities or contrast media, premedication, and desensitization.</p> </abstract>

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Section: Contrast Hypersensitivity Preventionmentioning

confidence: 99%

Contrast allergies for neurological imaging: When to proceed

Fusco

Pucci

Pierre

et al. 2022

ALLERGY

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“…A solution of iodine compounds is the most common commercially available X-ray contrast agent. However, as several researchers have pointed out, iodine compounds can cause allergic reactions in patients [4][5][6]. In addition to iodine-based contrast agents, Au is used as a contrast agent because it absorbs X-rays well and is less toxic than iodine compounds.…”

Section: Introductionmentioning

confidence: 99%

Synthesis of Single Nanometer-Sized Au Nanoparticles Coated with Silica Toward X-Ray Contrast Agent

Sakamoto,

Yamauchi,

Takase

et al. 2023

SSP

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In this study, we proposed a method for fabricating diagnostic imaging nanoparticles composed of Au nanoparticles and silica shells (Au/SiO2). The proposed method consisted of two steps. The first step was the synthesis of Au nanoparticles. In sodium hydroxide (NaOH) solution, hydrogen tetrachloroaurate (III) trihydrate was reduced with tetrakis(hydroxymethyl)phosphonium chloride to synthesize Au nanoparticles with a diameter of 1.7 ± 0.3 nm. The Au nanoparticles were then coated with silica in the following step. The silica coating was achieved via a sol–gel reaction of tetraethyl orthosilicate in the presence of Au nanoparticles in water/ethanol dissolved in NaOH. The Au/SiO2 nanoparticles degraded faster in saline or phosphate-buffered saline than in water, and the X-ray imaging capability was retained.

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