Patients’ experience and utilization patterns of diclofenac gel in Germany: a real-world study with a prospective longitudinal survey and a retrospective analysis of pharmacy data

Maihöfner, Christian; de Haas, Anke; Sethi, Vidhu; Shanga, Gilbert; Wilcox, Teresa K.; Csoke, Emese; Fabrikant, Kate

doi:10.1080/03007995.2023.2243804

Current Medical Research and Opinion

2023

DOI: 10.1080/03007995.2023.2243804

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Patients’ experience and utilization patterns of diclofenac gel in Germany: a real-world study with a prospective longitudinal survey and a retrospective analysis of pharmacy data

Christian Maihöfner,

Anke de Haas,

Vidhu Sethi

et al.

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Cited by 2 publications

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Guest editor foreword: real-world evidence and medical affairs

Jandhyala

2023

Current Medical Research and Opinion

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Guest editor foreword: real-world evidence and medical affairs

Jandhyala

2023

Current Medical Research and Opinion

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Real-world evidence evaluation on consumer experience and prescription journey of diclofenac gel in Sweden

Nair,

Norrefalk,

Csoke

et al. 2024

Scandinavian Journal of Pain

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Objectives The aim of this study was to understand profiles of topical Voltaren gel diclofenac (VGD) 2.32 and 1.16% consumers through analyzing prescription patterns and to characterize treatment satisfaction, functional impairment, and pain relief after over-the-counter (OTC) VGD use in Sweden under real-world conditions. Methods This observational, real-world study conducted in Sweden had retrospective and prospective segments. The retrospective secondary data segment utilized 12-month diclofenac gel prescription data from the Swedish eHealth Agency (E-hälsomyndigheten). The prospective segment included electronic surveys completed at baseline and weeks 4 and 12 by adult consumers who purchased OTC VGD to treat their pain. Results Secondary data analyses (n = 12,145) showed that 56.7% of patients receiving diclofenac gel were females ≥70 years old. Most patients did not switch pain treatments; the mean time between diclofenac gel refills was about 2.5 months. From the surveys (n = 264), VGD provided pain relief, indicated by improvement in 11-point pain numeric rating scale scores. Average pain severity at baseline was 5.8 – improving by a mean of 1.3 and 1.9 points at weeks 4 and 12, respectively. The majority of consumers reported improvement in daily functioning (i.e., health-related quality of life [HRQoL]), and most were at least somewhat satisfied with VGD treatment results. Conclusions This real-world study provides important insights into the prescription patterns of diclofenac gel and the consumer experience with OTC VGD in Sweden. Patients rarely switched to other topical nonsteroidal anti-inflammatory drugs, and VGD consumers reported pain relief and improved HRQoL compared to baseline – resulting in treatment satisfaction.

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Patients’ experience and utilization patterns of diclofenac gel in Germany: a real-world study with a prospective longitudinal survey and a retrospective analysis of pharmacy data

Cited by 2 publications

References 40 publications

Guest editor foreword: real-world evidence and medical affairs

Guest editor foreword: real-world evidence and medical affairs

Real-world evidence evaluation on consumer experience and prescription journey of diclofenac gel in Sweden

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