Patients’ Behavior Regarding Dietary or Herbal Supplements before and during COVID-19 in Saudi Arabia

Abstract

The use of traditional medicinal plants in Saudi Arabia stems mainly from consumers’ belief in prophetic medicine. This study was conducted to explore changes in patients’ use of dietary or herbal supplements among individuals infected with COVID-19 before and during infection and the association between herbal or dietary supplements and hospitalization. A cross-sectional, questionnaire-based study was conducted enrolling symptomatic patients who had recently recovered from COVID-19. Data were collected through phone interviews, and McNemar’s test was used to investigate changes to consumption of dietary or herbal supplements before and during infection. Multivariable logistic regression was used to investigate the association between supplements use during patients’ infection and hospitalization. A total of 738 patients were included in this study, of whom 32.1% required hospitalization. About 57% of participants were male with a mean age of 36.5 (±11.9) years. The use of lemon/orange, honey, ginger, vitamin C, and black seed among participants significantly increased during their infection. In contrast, patients using anise, peppermint, and coffee peel before their infection were more likely to stop using them during their infection. In addition, using lemon/orange (p < 0.0001), honey (p = 0.0002), ginger (p = 0.0053), vitamin C (p = 0.0006), black seed (p < 0.0001), peppermint (p = 0.0027), costus (p = 0.0095), and turmeric (p = 0.0012) was significantly higher among nonhospitalized patients than hospitalized ones. However, in the multivariable logistic regression, only use of vitamin C (OR = 0.51; 95% CI 0.33–0.79), peppermint (OR = 0.53; 95% CI 0.31–0.90), and lemon/orange (OR = 0.54; 95% CI 0.33–0.88) was associated with significantly lower odds of hospitalization. The study reveals that patients’ consumption of dietary or herbal supplements changed in response to their COVID-19 infection, with hospitalized patients having a lower likelihood of using these supplements. Because some supplements were associated with lower odds of hospitalization, these supplements or their bioactive components should be further investigated as feasible options for COVID-19 treatment.

Association of Healthy Diet with Recovery Time from COVID-19: Results from a Nationwide Cross-Sectional Study

“…Patient demographics are given in Table 1. [21]. Data presented as frequency (%) unless otherwise indicated.…”

“…Conversely, malnutrition is detrimental to health status, increasing the susceptibility to (and slowing the recovery from) infections [18,19]. Evidence has emphasized the vital role of dietary habits in altering patients' prevalence and severity of, and the speed of recovery from, infectious diseases [14,20,21]. Comprehensive eating plans such as the traditional Mediterranean diet, which consist of healthy foods, can support the immune system's response to infections [20].…”

Use of Traditional, Complementary and Integrative Medicine During the COVID-19 Pandemic: A Systematic Review and Meta-Analysis

“…Twenty-two studies were conducted in China ( 27 , 31 – 34 , 37 , 39 , 40 , 44 , 47 , 55 , 62 – 65 , 67 , 69 – 73 , 75 – 77 ), six in Saudi Arabia ( 18 , 21 – 23 , 25 , 26 ), five in India ( 10 , 41 , 46 , 60 , 61 ), three in the United States ( 35 , 42 , 45 ) and three in Turkey ( 38 , 49 , 66 ), and these were the most frequent countries included in this review. Among the population-based survey studies, thirty-one were conducted through online surveys only ( 17 , 18 , 20 , 22 , 23 , 25 , 26 , 28 – 31 , 35 , 42 , 43 , 45 , 48 – 54 , 57 – 62 , 66 , 68 , 74 ), one was an in-person interview ( 56 ), three were telephone interviews ( 10 , 21 , 38 ), and two were both in-person and online surveys ( 19 , 36 ). Among the included studies, usage status of the interventions, including TCM ( n = 22) ( 27 , 32 – 34 , 37 , 39 , ...…”

“…Most of the data for surveys or patient chart reviews were collected during 2020. In approximately half of the studies, TCIM interventions were used for prophylactic purposes ( n = 28) ( 17 – 20 , 22 , 23 , 25 , 26 , 28 , 31 , 35 , 36 , 38 , 41 , 42 , 45 , 48 – 54 , 59 , 61 , 62 , 66 , 74 ), and the other half were used for therapeutic purposes ( n = 27) ( 21 , 24 , 27 , 32 – 34 , 37 , 39 , 40 , 44 , 46 , 47 , 55 , 58 , 63 – 65 , 67 , 69 – 73 , 75 – 77 ) ( Table 1 ).…”

Deciphering the immunoboosting potential of macro and micronutrients in COVID support therapy

“…Vitamin C cannot synthesize in the body because of the absence of the enzyme that is a key factor for its de novo biosynthesis. It blocks oxidative stresses via reduction or prevention of generation of reactive oxygen and nitrogen species (Xu et al 2021 ; Aldwihi et al 2021 ). Vitamin C provides support to the immune system, protecting it against the coronavirus.…”