Patient-specific indirectly 3D printed mitral valves for pre-operative surgical modelling

Ginty, Olivia K.; Moore, John; Xia, Wenyao; Bainbridge, Daniel; Peters, Terry M.

doi:10.1117/12.2255567

Cited by 6 publications

(5 citation statements)

References 20 publications

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“…The valves act as important landmarks and guides during beating heart interventions, so it is important that the models still contain valves to aid clinicians in interpreting the patient's anatomy and for guiding the catheter within the model. To overcome this, we have developed a methodology for creating both patient-specific 33 and generalized valve models. As we did not have a TEE scan from this patient, a different patient's TEE scan, acquired in systole, was used to generate a mitral valve model, with the only modification being scaling of the computational model to fit the other patient.…”

Section: Valve Manufacturingmentioning

confidence: 99%

Patient-specific cardiac phantom for clinical training and preprocedure surgical planning

et al. 2018

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Minimally invasive mitral valve repair procedures including MitraClip are becoming increasingly common. For cases of complex or diseased anatomy, clinicians may benefit from using a patient-specific cardiac phantom for training, surgical planning, and the validation of devices or techniques. An imaging compatible cardiac phantom was developed to simulate a MitraClip procedure. The phantom contained a patient-specific cardiac model manufactured using tissue mimicking materials. To evaluate accuracy, the patient-specific model was imaged using computed tomography (CT), segmented, and the resulting point cloud dataset was compared using absolute distance to the original patient data. The result, when comparing the molded model point cloud to the original dataset, resulted in a maximum Euclidean distance error of 7.7 mm, an average error of 0.98 mm, and a standard deviation of 0.91 mm. The phantom was validated using a MitraClip device to ensure anatomical features and tools are identifiable under image guidance. Patient-specific cardiac phantoms may allow for surgical complications to be accounted for preoperative planning. The information gained by clinicians involved in planning and performing the procedure should lead to shorter procedural times and better outcomes for patients.

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Section: Valve Manufacturingmentioning

confidence: 99%

Patient-specific cardiac phantom for clinical training and preprocedure surgical planning

et al. 2018

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“…13 While providing adequate representation of cardiac surface anatomy, computational models developed from in vivo imaging using echocardiography, magnetic resonance imaging, and computed tomography are limited by the resolution required to segment the internal cardiac anatomy including atrioventricular valves and their corresponding subvalvular apparatuses in a way that accurately represents their details and variations. 14 In using mCT, albeit ex vivo, we can generate computational models with logarithmically higher resolution and detail. In this instance, the authors acknowledge that, to date, we are unable to create these high-resolution images in vivo as we are unable to place humans in mCT machines, and as we have not animated these models, the myocardium and valves can only be visualized in a static position.…”

Section: Discussionmentioning

confidence: 99%

A High-Fidelity Three-Dimensional Computational Model of a Patient with Hypertrophic Cardiomyopathy

Arango

Díaz-Gómez

Iaizzo

et al. 2022

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“…However, different test systems have different requirements for blood mimicking fluids. When using Doppler ultrasound, the addition of 5 μm diameter nylon scattering particles to a fluid matrix containing water, glycerol, dextran, and surfactants improves the acoustic properties of the fluid and provides better imaging [80]. Velocity measurement using particle images requires the addition of tracer particles to the fluid.…”

Section: Blood Mimicking Fluidmentioning

confidence: 99%

Three-dimensional printing for cardiovascular diseases: from anatomical modeling to dynamic functionality

et al. 2020

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Three-dimensional (3D) printing is widely used in medicine. Most research remains focused on forming rigid anatomical models, but moving from static models to dynamic functionality could greatly aid preoperative surgical planning. This work reviews literature on dynamic 3D heart models made of flexible materials for use with a mock circulatory system. Such models allow simulation of surgical procedures under mock physiological conditions, and are; therefore, potentially very useful to clinical practice. For example, anatomical models of mitral regurgitation could provide a better display of lesion area, while dynamic 3D models could further simulate in vitro hemodynamics. Dynamic 3D models could also be used in setting standards for certain parameters for function evaluation, such as flow reserve fraction in coronary heart disease. As a bridge between medical image and clinical aid, 3D printing is now gradually changing the traditional pattern of diagnosis and treatment.

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Patient-specific indirectly 3D printed mitral valves for pre-operative surgical modelling

Cited by 6 publications

References 20 publications

Patient-specific cardiac phantom for clinical training and preprocedure surgical planning

Patient-specific cardiac phantom for clinical training and preprocedure surgical planning

A High-Fidelity Three-Dimensional Computational Model of a Patient with Hypertrophic Cardiomyopathy

Three-dimensional printing for cardiovascular diseases: from anatomical modeling to dynamic functionality

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