Patient-Specific 3D-Printed Models in Pediatric Congenital Heart Disease

Sun, Zhonghua

doi:10.3390/children10020319

Cited by 8 publications

(8 citation statements)

References 107 publications

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“…CHD presents a formidable challenge due to the intricate nature of anatomical anomalies, the diverse spectrum of conditions, and individual variations [16]. Utilizing 3D-printed physical models, derived from patient imaging data, can significantly enhance comprehension of complex anatomical structures [17].…”

Section: Discussionmentioning

confidence: 99%

Integration of case-based learning and three-dimensional printing for tetralogy of fallot instruction in clinical medical undergraduates: a randomized controlled trial

Zhao,

Gong,

Ding

et al. 2024

BMC Med Educ

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Background Case-based learning (CBL) methods have gained prominence in medical education, proving especially effective for preclinical training in undergraduate medical education. Tetralogy of Fallot (TOF) is a congenital heart disease characterized by four malformations, presenting a challenge in medical education due to the complexity of its anatomical pathology. Three-dimensional printing (3DP), generating physical replicas from data, offers a valuable tool for illustrating intricate anatomical structures and spatial relationships in the classroom. This study explores the integration of 3DP with CBL teaching for clinical medical undergraduates. Methods Sixty senior clinical medical undergraduates were randomly assigned to the CBL group and the CBL-3DP group. Computed tomography imaging data from a typical TOF case were exported, processed, and utilized to create four TOF models with a color 3D printer. The CBL group employed CBL teaching methods, while the CBL-3DP group combined CBL with 3D-printed models. Post-class exams and questionnaires assessed the teaching effectiveness of both groups. Results The CBL-3DP group exhibited improved performance in post-class examinations, particularly in pathological anatomy and TOF imaging data analysis (P < 0.05). Questionnaire responses from the CBL-3DP group indicated enhanced satisfaction with teaching mode, promotion of diagnostic skills, bolstering of self-assurance in managing TOF cases, and cultivation of critical thinking and clinical reasoning abilities (P < 0.05). These findings underscore the potential of 3D printed models to augment the effectiveness of CBL, aiding students in mastering instructional content and bolstering their interest and self-confidence in learning. Conclusion The fusion of CBL with 3D printing models is feasible and effective in TOF instruction to clinical medical undergraduates, and worthy of popularization and application in medical education, especially for courses involving intricate anatomical components.

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Section: Discussionmentioning

confidence: 99%

Integration of case-based learning and three-dimensional printing for tetralogy of fallot instruction in clinical medical undergraduates: a randomized controlled trial

Zhao,

Gong,

Ding

et al. 2024

BMC Med Educ

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“…Three-dimensionally printed models improve communication between clinicians and patients, as well as communication between clinical colleagues. Owing to the development of more 3D printing materials that are able to simulate cardiovascular tissue properties (Figure 34) [215], more flexible and realistic 3D models could be printed in the future to further advance the efficacy of using 3D printing technology in cardiovascular disease by, for example, carrying out simulations of cardiovascular hemodynamics related to cardiovascular disease. Clinical studies, in particular longitudinal follow-ups on the impact of using 3D-printed models on patients' clinical outcomes and cost-effectiveness, are still lacking, and these topics should remain the focus of further studies.…”

Section: Summary Concluding Remarks and Future Directionsmentioning

confidence: 99%

Cardiovascular Computed Tomography in the Diagnosis of Cardiovascular Disease: Beyond Lumen Assessment

Sun,

Silberstein,

Vaccarezza

2024

JCDD

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Cardiovascular CT is being widely used in the diagnosis of cardiovascular disease due to the rapid technological advancements in CT scanning techniques. These advancements include the development of multi-slice CT, from early generation to the latest models, which has the capability of acquiring images with high spatial and temporal resolution. The recent emergence of photon-counting CT has further enhanced CT performance in clinical applications, providing improved spatial and contrast resolution. CT-derived fractional flow reserve is superior to standard CT-based anatomical assessment for the detection of lesion-specific myocardial ischemia. CT-derived 3D-printed patient-specific models are also superior to standard CT, offering advantages in terms of educational value, surgical planning, and the simulation of cardiovascular disease treatment, as well as enhancing doctor–patient communication. Three-dimensional visualization tools including virtual reality, augmented reality, and mixed reality are further advancing the clinical value of cardiovascular CT in cardiovascular disease. With the widespread use of artificial intelligence, machine learning, and deep learning in cardiovascular disease, the diagnostic performance of cardiovascular CT has significantly improved, with promising results being presented in terms of both disease diagnosis and prediction. This review article provides an overview of the applications of cardiovascular CT, covering its performance from the perspective of its diagnostic value based on traditional lumen assessment to the identification of vulnerable lesions for the prediction of disease outcomes with the use of these advanced technologies. The limitations and future prospects of these technologies are also discussed.

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“…One of our studies showed that a low-cost CHD model printed with a relatively cheap material produced a similar clinical value as the high-cost model [ 26 , 50 , 51 ]. Figure 8 shows a 3D-printed CHD (double outlet right ventricle) model using low-cost thermoplastic polyurethane (TPU, USD 25) and relatively high-cost TangoPlus (USD 200) materials.…”

Section: Usefulness Of 3d-printed Models In Cardiovascular Diseasementioning

confidence: 99%

“…Arrows refer to subaortic ventricular septal defect. Reprinted with permission under the open access from Sun [ 51 ].…”

Section: Figurementioning

confidence: 99%

Patient-Specific 3D-Printed Low-Cost Models in Medical Education and Clinical Practice

2023

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3D printing has been increasingly used for medical applications with studies reporting its value, ranging from medical education to pre-surgical planning and simulation, assisting doctor–patient communication or communication with clinicians, and the development of optimal computed tomography (CT) imaging protocols. This article presents our experience of utilising a 3D-printing facility to print a range of patient-specific low-cost models for medical applications. These models include personalized models in cardiovascular disease (from congenital heart disease to aortic aneurysm, aortic dissection and coronary artery disease) and tumours (lung cancer, pancreatic cancer and biliary disease) based on CT data. Furthermore, we designed and developed novel 3D-printed models, including a 3D-printed breast model for the simulation of breast cancer magnetic resonance imaging (MRI), and calcified coronary plaques for the simulation of extensive calcifications in the coronary arteries. Most of these 3D-printed models were scanned with CT (except for the breast model which was scanned using MRI) for investigation of their educational and clinical value, with promising results achieved. The models were confirmed to be highly accurate in replicating both anatomy and pathology in different body regions with affordable costs. Our experience of producing low-cost and affordable 3D-printed models highlights the feasibility of utilizing 3D-printing technology in medical education and clinical practice.

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Patient-Specific 3D-Printed Models in Pediatric Congenital Heart Disease

Cited by 8 publications

References 107 publications

Integration of case-based learning and three-dimensional printing for tetralogy of fallot instruction in clinical medical undergraduates: a randomized controlled trial

Integration of case-based learning and three-dimensional printing for tetralogy of fallot instruction in clinical medical undergraduates: a randomized controlled trial

Cardiovascular Computed Tomography in the Diagnosis of Cardiovascular Disease: Beyond Lumen Assessment

Patient-Specific 3D-Printed Low-Cost Models in Medical Education and Clinical Practice

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