Patient Reporting of Adverse Drug Reactions (ADRs): Survey of Public Awareness and Predictors of Confidence to Report

Hariraj, Vidhya; Aziz, Zoriah

doi:10.1177/2168479017745025

Cited by 13 publications

(16 citation statements)

References 25 publications

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“…The causes of acute drug poisoning in adults are complex, which are often related to the lack of awareness of personal medication safety and the toxic effects of the drug itself [ 1 ]. It refers to a drug poisoning event in which toxic drugs enter the human body through the respiratory tract, skin, mucous membrane, or digestive tract in a short time, causing damage to the patient's body and occurrence of multiple organ dysfunction, which has the characteristics of rapid onset, severe illness, and high mortality [ 2 , 3 ]. In recent years, its incidence in China has increased, accounting for about 6% to 8% of the total number of patients in the emergency department, which puts pressure on the diagnosis and treatment of the emergency department.…”

Section: Introductionmentioning

confidence: 99%

Analysis of Influencing Factors of Acute Medication Poisoning in Adults in Emergency Department of Our Hospital from 2016 to 2019 and Observation of Curative Effect of Optimizing Emergency Procedures

Bian

Zhu

Han

et al. 2021

Evidence-Based Complementary and Alternative Medicine

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Objective. This study analyzed the influencing factors of acute medication poisoning in adults in the emergency department of our hospital from January 2016 to December 2019 and observed the curative effect of optimizing emergency procedures on adult acute medication poisoning. Our results showed that, among all acute drug poisoning patients, the most common poisoning drug was sleeping pills (24.22%), followed by painkillers (20.31%) and antipsychotics (16.41%). Education level, drug category, drug source, drug dosage, unknown drug composition, and medication side effect were all influencing factors of acute drug poisoning. High school education level or below, self-purchasing medicine, medication overdose, unknown drug composition, and medication side effect were the risk factors of acute medication poisoning. In addition, after the nursing management of optimizing emergency procedures for this type of patients, the rescue time, observation time, and hospital stay of the patients had been shortened, the incidence of complications was low, the rescue success rate was high, and the clinical application effect was good.

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Section: Introductionmentioning

confidence: 99%

Analysis of Influencing Factors of Acute Medication Poisoning in Adults in Emergency Department of Our Hospital from 2016 to 2019 and Observation of Curative Effect of Optimizing Emergency Procedures

Bian

Zhu

Han

et al. 2021

Evidence-Based Complementary and Alternative Medicine

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“…We used the significant level at p < 0.1 to select variables for the univariate logistic regression analysis because, at a level of p < 0.05, variables known to be important would have been excluded [ 33 ]. Several other studies [ 34 – 36 ] also used the same level ( p < 0.01). Non-ordered categorical data with more than two levels (e.g.…”

Section: Methodsmentioning

confidence: 99%

Disposal practice and factors associated with unused medicines in Malaysia: a cross-sectional study

2021

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Background The improper disposal of unused medicines is a worldwide concern because of its impact on the environment, economy, and health. This study aims to describe the disposal practice of unused medicine and identify factors associated with unused medicines in Malaysia. Methods This was a cross-sectional, face to face interview-based survey using a structured questionnaire. We used a convenience sampling method to recruit participants from Kuala Lumpur and Selangor in Malaysia. Results We interviewed 1184 participants, and the response rate was 96%. Out of the total respondents, 995 (84%) reported having unused medicines. About a quarter of respondents kept unused medicines in the cabinet, and another quarter disposed of them into the trash or toilet. Only half of the respondent who used medicines for chronic illnesses had unused medicines compared to about 90% of respondents who used medicines for acute illnesses. The main reason for having unused medicines among those who used medicines for chronic illness was non-adherence (69%, p < 0.05). Only 27% of these respondents returned unused medicines under the “Medicine Return Programme (MRP)”. The other group who used medicines for acute illnesses had unused medicines because their health conditions improved. Thus, most of the unused medicines will eventually end up in household waste. A multivariate logistic regression analysis identified respondents who used medicines for acute illnesses as the strongest predictor of having unused medicines (Odds Ratio (OR) = 29.8; p < 0.001), followed by those who pay for their medicines (OR = 6.0; p < 0.001) and those who were willing to participate the Medicine Return Programme (OR = 2.5; p = 0.009). Conclusion The prevalence of unused medicines and their improper disposal were high in Malaysia. Unused medicines are associated with people who use medicines for acute illnesses, pay for their medication, and are willing to participate in an MRP. Rationale prescription and optimal dispensing practice, together with a broader MRP facilities coverage, could reduce unused medicine possession.

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“…Through the questionnaire survey, it can be said respondents' knowledge of ADR and its monitoring and reporting was incomplete. Other studies have shown similar results [29,35]. Studies [9,[39][40][41] show that the public (patients) and HCPs often ignore the criteria of reporting an ADR immediately upon suspecting an ADR, many individuals think that only serious ADRs that affect daily life or require hospitalization are worth reporting, or they only selectively report new ADRs, which will lead to underreporting.…”

Section: Discussionmentioning

confidence: 81%

“…ADRs reported by the public can complement those reported by HCPs, to add value to the pharmacovigilance system and generate new safety signals [6,18,19]. Globally, more than 40 countries have incorporated patient or consumer ADR reporting into their pharmacovigilance schemes [29,30]. In some countries like the United States, Canada, and New Zealand, consumers have been allowed to directly report ADRs since implementation of the pharmacovigilance plan [14,31].…”

Section: Introductionmentioning

confidence: 99%

A cross-sectional study: comparison of public perceptions of adverse drug reaction reporting and monitoring in eastern and western China

Ning-sheng

Chen

Ren

et al. 2022

BMC Health Serv Res

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Background Adverse drug reactions (ADRs) cause a substantial clinical and economic burden. Spontaneous reporting of ADRs by the public is crucial. In some developed countries like the United States, Canada, consumers have been allowed to directly report ADRs, however, convenient channels for direct ADR reporting by the public are lacking in China. Objective We aimed to compare the knowledge, attitudes, and practice(KAP) regarding monitoring and reporting of adverse drug reaction (ADR) among the general public in eastern and western China. Methods A questionnaire-guided cross-sectional study was administered to participants in Nanjing and Xi’an during April–July 2019. A descriptive statistical analysis was used to describe respondents’ demographic information and other results. The t-test and analysis of variance were used to test the differences in knowledge and attitudes among respondents with different demographic characteristics. P < 0.05 was considered statistically significant. Binary logistic regression analysis was used to examine factors associated with knowledge and attitudes. Results A total of 1085 questionnaires were distributed in this survey, 869 valid questionnaires were returned, the recovery rate was 80.09%. Respondents showed poor knowledge of the definition of ADRs and reporting criteria, with a significant difference in average knowledge scores according to education level, gender, and age group. Most respondents had positive attitudes toward ADR monitoring and reporting, with no significant differences in knowledge and attitude scores between the two cities. In total, 68.93% of respondents said they would feedback information to health care professionals, most (84.35%) would take the initiative to report ADRs if there were a convenient method. More than half (58.57%) of respondents were more likely to report ADRs by telephone. Conclusion The findings of our study indicated that health care professionals should encourage patients to actively report ADR. China should also explore ways to facilitate direct public reporting of ADRs by improving relevant laws and regulations.

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Patient Reporting of Adverse Drug Reactions (ADRs): Survey of Public Awareness and Predictors of Confidence to Report

Cited by 13 publications

References 25 publications

Analysis of Influencing Factors of Acute Medication Poisoning in Adults in Emergency Department of Our Hospital from 2016 to 2019 and Observation of Curative Effect of Optimizing Emergency Procedures

Analysis of Influencing Factors of Acute Medication Poisoning in Adults in Emergency Department of Our Hospital from 2016 to 2019 and Observation of Curative Effect of Optimizing Emergency Procedures

Disposal practice and factors associated with unused medicines in Malaysia: a cross-sectional study

A cross-sectional study: comparison of public perceptions of adverse drug reaction reporting and monitoring in eastern and western China

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