Patient-Reported Outcomes With Vitamin E and Pentoxifylline after Post-Mastectomy Radiation (PMRT) and Reconstruction; Initial Results From a Prospective Pilot Trial
Abstract:Purpose/Objective(s): Oral vitamin E and pentoxifylline have been used to decrease fibrosis after breast-conserving surgery and radiation therapy. The hypothesis was that this regimen would improve patient-reported outcomes and implant failure rates. Materials/Methods: Women who underwent PMRT after implant-based reconstruction were eligible. Subjects were given oral vitamin E 400 IU daily and pentoxifylline 400 mg twice daily for 1 week and if tolerated were increased to 400 mg thrice daily. Vitamin E and pen… Show more
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