Patient-Reported Outcomes of Regular Aerobic Exercise in Gastric Cancer

Abstract

The benefits of exercise for health-related quality of life (HRQOL) and depression in patients with gastrointestinal disease remain unclear, and studies on gastric cancer are scant. This study examines the association between the maintenance of regular aerobic exercise at a recommended level and depression and HRQOL in patients with gastric cancer during or after treatment. In this cross-sectional study, a face-to-face survey was used to collect data from 126 patients with primary gastric cancer during or after treatment in a tertiary acute-care hospital in Korea. Regular exercise was defined as regularly maintained aerobic exercise of at least moderate intensity consuming ≥4 metabolic equivalents for ≥150 min/wk for at least 6 months. Depression was measured using the 9-item version of the Patient Health Questionnaire, and HRQOL was assessed using the EORTC QLQ-C30. Patients who maintained aerobic exercise at a recommended level were less likely to have depression and more likely to have improved global QOL, as well as physical, role, and emotional functioning. Patients with depression were less likely to report improved global QOL and functioning. Thus, exercise can have a synergistic effect on improvement in HRQOL via indirect positive effects on depression and direct effects on HRQOL in patients with gastric cancer. Oncology nurses should encourage patients with gastric cancer who suffer from a depressive mood to set up and implement specific plans for practicing regular exercise, which can lead to an improvement in both depression and HRQOL.

Effect of HCH Nutrition Management Combined with Early Exercise Nursing on Nutrition Status and Postoperative Rehabilitation of Patients after Gastric Cancer Surgery

“…Furthermore, early exercise can promote gastrointestinal peristalsis and friction between intestinal loops, and reduce the resistance between the gastrointestinal tract and peritoneum, mesentery, and other tissues, so as to maintain stable visceral activities, reduce gastrointestinal discomfort, and facilitate postoperative rehabilitation of patients as soon as possible after surgery. Meanwhile, malnutrition is a common complication of cancer patients, with an incidence of up to 67%, especially in gastrointestinal tumor patients, with a higher incidence of malnutrition [ 11 ]. Nutrition management is an important method for maintaining the tumor patient's nutrition status.…”

Patient reported outcomes in oncology: changing perspectives—a systematic review

“…Five main advantages related with cancer patients are consistently and actually presented in literature regarding PRO incorporation in daily clinical practice. They are: (1) stepped care models design reflecting patient’s disease pathway [ 4 , 5 , 31 , 32 , 34 , 36 – 57 ] (2) prognosis value [ 2 – 4 , 22 , 31 , 34 , 37 – 43 , 47 , 50 , 53 , 57 – 74 ] (3) communication improvements [ 4 , 5 , 10 , 22 , 31 , 32 , 34 , 36 , 38 , 40 – 43 , 46 – 50 , 53 , 55 , 65 – 69 , 71 – 82 ], (4) patient safety optimization [ 4 , 5 , 10 , 30 , 31 , 34 , 36 , 39 – 43 , 47 , 48 , 52 , 53 , 55 , 56 , 60 – 62 , 64 – 66 , 68 , 70 , 72 – 74 , 77 – 87 ] and (5) healthcare risk identification, i.e., unmet problems identification, symptom detection and symptom control [ 2 ,…”

“…identified key areas of improvement and confirmed that well-conducted and reported prognostic model studies with a PRO predictor have great potential to improve healthcare delivery [ 38 ]. The physical functioning, global health and QoL domains were consider significant prognostic factors (prognosticators) and several domains have been evidenced [ 39 , 40 , 43 ] including patient-reported functional scores [ 37 , 42 , 60 , 61 , 63 , 68 ], patient-reported symptom interference [ 38 , 49 , 59 , 62 , 65 , 66 ], patient-reported depression [ 96 ], or patient-reported fatigue [ 67 , 69 ].…”

“…The present study reports that PROs can capture patient’s essentials on disease pathway. They are crucial at baseline and follow-up stages and consistently consider them in research and clinical practice is a major concern for future in health systems [ 31 – 34 , 37 – 42 , 50 , 51 , 59 – 63 , 65 , 66 , 69 , 77 , 88 , 93 , 94 , 97 – 99 ].…”

Lower risk of depression after smoking cessation and alcohol abstinence in patients with gastric cancer who underwent gastrectomy: A population‐based, nationwide cohort study

“…Lifestyle behaviors, such as smoking, [14][15][16][17][18] alcohol intake, [18][19][20][21][22][23] and physical inactivity, 18,[24][25][26][27] have been associated with a high risk of depression. Smoking might lead to depression through effects on the neurotransmitter system, which increases susceptibility to environmental stressors.…”