Patient‐reported outcomes of blue‐light flexible cystoscopy with hexaminolevulinate in the surveillance of bladder cancer: results from a prospective multicentre study

Abstract

Anxiety decreased after BLFC in patients with negative pathology, including patients with false-positive results. Most of the patients undergoing BLFC were willing to pay out of pocket, found the procedure worthwhile and would recommend it to others, irrespective of whether they had a positive BLFC result or whether this was false-positive after surgery.

Performance of Narrow Band Imaging (NBI) and Photodynamic Diagnosis (PDD) Fluorescence Imaging Compared to White Light Cystoscopy (WLC) in Detecting Non-Muscle Invasive Bladder Cancer: A Systematic Review and Lesion-Level Diagnostic Meta-Analysis

“…Although PDD has a higher upfront cost, previous studies have found that, due to improved tumor detection and more complete resection, PDD is more cost-effective than WLC in the long term [37,42]. Even in the short term, Smith et al found that patients were willing to pay out-of-pocket despite the increased cost of PDD and demonstrated positive perceptions of PDD regardless of oncologic outcomes [43]. Sievert et al found that the TURB cost for conventional WLC was EUR 1527.11 (USD 2031.06), while PDD had a cost of EUR 1386.83 (USD 1844.48) with a net cost saving of EUR 140.28 (USD 168.57) in a German health system [44].…”

Blue light flexible cystoscopy with hexaminolevulinate in non-muscle-invasive bladder cancer: review of the clinical evidence and consensus statement on optimal use in the USA — update 2018

“…1.92)) and postoperating room (1.4 (s.d. 2.13)) 35 . Anxiety decreased uniformly after BLFC (Δ = -2.6), with no differences on the basis of gender, BLFC results (positive or negative) or test performance (false positive or true positive).…”

“…C o n S e n S u S S tat e m e n t baseline, immediately following surveillance cystoscopy and, for those referred to the operating room, after they had received the pathology findings and were aware of their diagnosis 35 . The Patient-Reported Outcomes Measurement Information System (PROMIS) Anxiety 4a form was used to measure anxiety and the PROMIS Pain Intensity 1a form was used to rank pain on a scale from 0 (no pain) to 10 (worst pain).…”

“…Most patients found BLFC "worthwhile", "would do it again" and "would recommend to others", with no differences on the basis of BLFC result or test performance. Furthermore, most patients (76%) were willing to pay themselves, with >50% willing to pay $100 or more for BLFC with HAL 35 .…”

The patient’s perspective on blue light flexible cystoscopy: insight from a prospective clinical study

“…Additionally, among patients with recurrent disease, blue light cystoscopy identified additional malignant lesions in 46% of patients. These investigators incorporated PRO measures in the trial design, allowing prospective study of satisfaction, anxiety, and willingness to pay among patients undergoing blue light flexible cystoscopy, the results of which were recently published by Smith and colleagues in BJU International (7). In this trial, all patients were administered questionnaires to assess anxiety and pain using validated questionnaires at the initial screening office visit and again immediately following surveillance BLFC.…”