Patient-Reported Outcomes Are Associated With Enhanced Recovery Status in Patients With Bladder Cancer Undergoing Radical Cystectomy

Kukreja, Janet Baack; Shi, Qiuling; Chang, Courtney M.; Seif, Mohamed; Sterling, Brandon; Chen, Ting Yu; Creel, Kelly M.; Kamat, Ashish M.; Dinney, Colin P.; Shah, Jay B.; Wang, Xin Shelley

doi:10.1177/1553350618764218

Cited by 25 publications

(10 citation statements)

References 33 publications

(37 reference statements)

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“…[12,13] Preoperative oral carbohydrate intake also improves patient-reported outcomes such as hunger before the induction of anesthesia. [14,15] In line with previous studies, the present study also showed that patients treated with preoperative oral carbohydrates had lower thirst and hunger scores. However, carbohydrates with potassium were not superior to carbohydrates without potassium in terms of prognosis, although they significantly reduced the incidence of preoperative hypokalemia without changing the flavor of the fluid.…”

Section: Discussionsupporting

confidence: 92%

Effects of preoperative oral carbohydrate electrolyte drinks on preoperative hypokalemia incidence in patients scheduled for laparoscopic colorectal resection: a randomized clinical trial

Tan

Deng

et al. 2020

Preprint

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Background:In our previous study, hypokalemia incidence was high in patients scheduled for laparoscopic colorectal resection. The present trial was conducted to verify the effects of preoperative carbohydrate drinks containing potassium in these patients. Methods: Patients were randomly assigned to control, placebo, and case groups. In control group, patients were fasted from midnight. In placebo group, patients were fasted from midnight and received carbohydrate drinks 2–3 h before surgery. In case group, patients were fasted from midnight and received carbohydrate drinks containing potassium supplementation 2–3 h before surgery. The primary outcome was the incidence and severity of preoperative hypokalemia. The other outcomes included postoperative gastrointestinal function, including the time to postoperative first flatus (FFL) and first feces (FFE) and other complications. Results: The final analysis included 122 participants. The incidence of preoperative hypokalemia in case group was significantly lower than that in control and placebo groups (50% vs. 88.1% vs. 77.5%, p < 0.001). The severity of hypokalemia in control and placebo groups was greater than that in case group. No regurgitation or aspiration occurred in the three groups. No significant differences were observed among the three groups regarding time to FFL and FFE. Conclusions: Preoperative carbohydrate drinks containing potassium may have significantly reduced the incidence of preoperative hypokalemia and improved preoperative thirst and hunger, but did not improve postoperative well-being. However, as part of the enhanced recovery after surgery protocol, preoperative carbohydrate drinks containing potassium should be recommended, as early as first admittance to hospital.

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Section: Discussionsupporting

confidence: 92%

Effects of preoperative oral carbohydrate electrolyte drinks on preoperative hypokalemia incidence in patients scheduled for laparoscopic colorectal resection: a randomized clinical trial

Tan

Deng

et al. 2020

Preprint

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show abstract

“…Patients with normal uid and electrolyte balance are likely to experience stable induction of anesthesia [12,13]. Preoperative oral carbohydrate intake also improves patient-reported outcomes such as hunger before the induction of anesthesia [14,15]. In line with previous studies, the present study also showed that patients treated with preoperative oral carbohydrates had lower thirst and hunger scores.…”

Section: Discussionsupporting

confidence: 88%

Effects of Preoperative Oral Carbohydrate Electrolyte Drinks on Preoperative Hypokalemia Incidence in Patients Scheduled for Laparoscopic Colorectal Resection: A Randomized Clinical Trial

Tan¹,

Deng²,

Hu³

et al. 2020

Preprint

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Background: In our previous study, hypokalemia incidence was high in patients scheduled for laparoscopic colorectal resection. The present trial was conducted to verify the effects of preoperative carbohydrate drinks containing potassium in these patients.Methods: Patients were randomly assigned to control, placebo, and case groups. In control group, patients were fasted from midnight. In placebo group, patients were fasted from midnight and received carbohydrate drinks 2–3 h before surgery. In case group, patients were fasted from midnight and received carbohydrate drinks containing potassium supplementation 2–3 h before surgery. The primary outcome was the incidence and severity of preoperative hypokalemia. The other outcomes included postoperative gastrointestinal function, including the time to postoperative first flatus (FFL) and first feces (FFE) and other complications. Results: The final analysis included 122 participants. The incidence of preoperative hypokalemia in case group was significantly lower than that in control and placebo groups (50% vs. 88.1% vs. 77.5%, p < 0.001). The severity of hypokalemia in control and placebo groups was greater than that in case group. No regurgitation or aspiration occurred in the three groups. No significant differences were observed among the three groups regarding time to FFL and FFE. Conclusions: Preoperative carbohydrate drinks containing potassium may have significantly reduced the incidence of preoperative hypokalemia and improved preoperative thirst and hunger, but did not improve postoperative well-being. However, as part of the enhanced recovery after surgery protocol, preoperative carbohydrate drinks containing potassium should be recommended, as early as first admittance to hospital. Trial registration: The study was registered with the Chinese Clinical Trial Registry at www.chictr.org on February 7, 2017 (registration number: ChiCTR-IOR-17010561).

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“…It has demonstrated differences in functional recovery following minimally invasive surgery versus thoracotomy for lung cancer [44]. In addition, it has been used to assess symptom severity before and after pelvic exenteration for a variety of gynecologic malignancies [45], early post-operative symptoms following radical cystectomy for bladder cancer [46], and other major abdominal cancer operations. The MDASI has also been used to compare symptom burden and functional recovery in ovarian cancer patients undergoing primary cytoreductive surgery compared to a neoadjuvant chemotherapy approach within an enhanced recovery after surgery (ERAS) program [47] as well as in patients undergoing hepatectomy under an ERAS program [48].…”

Section: Cancer and Disease Specific Instrumentsmentioning

confidence: 99%

Patient-Reported Outcomes in Surgical Oncology: An Overview of Instruments and Scores

Phillips

Wong

2019

Ann Surg Oncol

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Traditional measures of quality and effectiveness in surgical oncology have focused on morbidity, mortality and, when available, recurrence rates. Measuring patient reported outcomes (PROs) has become more widely accepted over the last decade. This article will review commonly used instruments in the surgical treatment of cancer patients to evaluate PROs. In addition, we will discuss the linkage of PROs and health-related quality of life measures with traditional surgical complications and highlight future directions related to the expanding use of PROs in the surgical care of cancer patients.

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Patient-Reported Outcomes Are Associated With Enhanced Recovery Status in Patients With Bladder Cancer Undergoing Radical Cystectomy

Abstract: These results suggest that ERAS practice significantly reduced immediate postoperative symptom burden in bladder cancer patients recovering from radical cystectomy, supporting the use of patient-reported symptom burden as an outcome measure in perioperative care.

Cited by 25 publications

References 33 publications

Effects of preoperative oral carbohydrate electrolyte drinks on preoperative hypokalemia incidence in patients scheduled for laparoscopic colorectal resection: a randomized clinical trial

Effects of preoperative oral carbohydrate electrolyte drinks on preoperative hypokalemia incidence in patients scheduled for laparoscopic colorectal resection: a randomized clinical trial

Effects of Preoperative Oral Carbohydrate Electrolyte Drinks on Preoperative Hypokalemia Incidence in Patients Scheduled for Laparoscopic Colorectal Resection: A Randomized Clinical Trial

Patient-Reported Outcomes in Surgical Oncology: An Overview of Instruments and Scores

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