Patient-Reported Outcome Measures May Add Value in Breast Cancer Surgery

Lagendijk, M.; Egdom, Laurentine S. E. van; Veen, F E E van; Vos, E L; Mureau, Marc A.M.; Leeuwen, Nikki van; Hazelzet, Jan A.; Lingsma, Hester F.; Koppert, Linetta B.

doi:10.1245/s10434-018-6729-6

Cited by 65 publications

(56 citation statements)

References 20 publications

(24 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The domain "Sexual Well-being" had a markedly lower median score of 58 and, furthermore, the response rate was low at 69.6%. This pattern has also been seen in previous studies investigating BCT [8,9,36], and it seems to be a general issue for this domain. Therefore, results must be interpreted with caution.…”

Section: Discussionsupporting

confidence: 86%

“…In the domain "Psychosocial Well-being" we found a median score of 82, similar to the results of O´Connell [8] and Dahlbäck [35], using Breast-Q™ for evaluation of the outcome of BCT, while Langendiik [36] found a mean score at 70.1 and Vesprini [9] found a mean score at 73.5. In our study we found a statistically significant better outcome for the OBS cohort, including level I and II surgery, compared with the BCS cohort.…”

Section: Discussionsupporting

confidence: 85%

“…In their analyses of the domain "Physical Well-being" after BCT with Breast-Q™, Langendjik [36] and Vesprini [9] found mean scores of 71.2 and 74, respectively. A slightly higher score of 75 was reported by O`Connell [8].…”

Section: Discussionmentioning

confidence: 99%

“…On the contrary, there was a slight difference in the figures, indicating better outcomes for OBS compared with BCS. In the analysis of the domain "Satisfaction with Breast" Vesprini [9] and Langendjik [36] found mean scores of 59.3 and 65.7, respectively, while Dahlbäck [35] and O´Connell [8] found median scores of 66 and 68, respectively. Hence, our median score of 74 in the present study means our scores are higher than those reported previously and they indicate a higher degree of satisfaction with the breast.…”

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Patient-reported outcome after oncoplastic breast surgery compared with conventional breast-conserving surgery in breast cancer

Rose

Svensson

Handler

et al. 2020

Breast Cancer Res Treat

View full text Add to dashboard Cite

Introduction Oncoplastic breast surgery (OBS) has developed as an extension of breast-conserving surgery (BCS) in an effort to improve esthetic and functional outcome following surgery for breast cancer. The aim of the present study was to evaluate the possible benefits of OBS, as compared with BCS, with regard to health-related quality of life (HRQoL), using patient-reported outcome measures (PROMs). Patients and methods Patients treated with OBS (n = 200) and BCS (n = 1304) in the period 1 January 2008 to 31 December 2013 were identified in a research database and in the Danish Breast Cancer Cooperative Group (DBCG) registry. Data on patient, tumor, and treatment characteristics were retrieved from the DBCG registry. Patients were sent a survey including the Breast-Q™ BCT postoperative module and a study-specific questionnaire (SSQ) in 2016. A good outcome in the Breast-Q module was defined as above the median. OBS was compared to BCS using a logistic regression analysis, and then adjusted for potential confounders, yielding odds ratios (OR) with 95% confidence intervals. Results There was a statistically significant better outcome considering the HRQoL domain "Psychosocial Well-being " for patients treated with OBS as compared with BCS (OR 2.15: 1.25-3.69). No statistically significant differences were found for the domains "Physical Well-being" (0.83: 0.50-1.39), "Satisfaction with Breast" (0.95: 0.57-1.59), or "Sexual Wellbeing" (1.42: 0.78-2.58). Conclusion The present study indicates better outcomes of HRQoL for breast cancer patients treated with OBS as compared to patients treated with BCS. There was no increase in physical discomfort among OBS patients despite more extensive surgery.Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

show abstract

Section: Discussionsupporting

confidence: 86%

Section: Discussionsupporting

confidence: 85%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Patient-reported outcome after oncoplastic breast surgery compared with conventional breast-conserving surgery in breast cancer

Rose

Svensson

Handler

et al. 2020

Breast Cancer Res Treat

View full text Add to dashboard Cite

show abstract

“…PRO measures have gained traction as components of value-based health care decision making, including in assessment of comparative effectiveness and shared decision-making support in areas such as breast cancer surgery. 19,20 There is even discussion of third-party payers incorporating PRO data into valuebased reimbursement schemes. 21 Standardized tools incorporating patients' perspectives have been developed and validated to assess QoL for patients with many conditions.…”

Section: Developing a Standardized Instrument For Ftmentioning

confidence: 99%

How to Integrate Lived Experience Into Quality-of-Life Assessment in Patients Considering Facial Transplantation

Kimberly¹,

Alfonso

Ramly

et al. 2019

AMA Journal of Ethics

View full text Add to dashboard Cite

DDSTo claim one AMA PRA Category 1 Credit TM for the CME activity associated with this article, you must do the following: (1) read this article in its entirety, (2) answer at least 80 percent of the quiz questions correctly, and (3) complete an evaluation. The quiz, evaluation, and form for claiming AMA PRA Category 1 Credit TM are available through the AMA Ed Hub TM . AbstractFacial transplantation has gained increasing acceptance as a treatment option to improve quality of life (QoL) for persons suffering from severe facial disfigurement. Despite its growth, the field has yet to establish a consistent approach to assessing QoL in face transplant candidates and recipients that includes integration of meaningful patient-reported outcomes. The published literature suggests that face transplant programs currently use a wide variety of assessment tools and strategies. Moreover, confusion remains as to how best to weigh patients' lived experiences and incorporate them into QoL assessments. Qualitative research can illuminate the dimensions of QoL that are meaningful to face transplant candidates and recipients. Coupled with collaboration and data sharing across face transplant programs, qualitative research will help to bring conceptual clarity and transparency to the assessment process. BackgroundPersons living with severe facial disfigurement, whether congenital or acquired, suffer not only from debilitating functional limitations-including difficulty speaking and swallowing-but also from intense social stigma related to their visible difference. Social stigma in the form of ostracism frequently leads to extreme social isolation and is associated with adverse mental health outcomes, including depression, anxiety, posttraumatic stress, and suicidal thoughts or actions. 1 Facial transplantation (FT) as a means of improving quality of life (QoL) can enable recipients to re-engage socially, restoring their social identities as active, integrated members of their communities. Bramstedt has even argued that severe facial disfigurement could be akin to a form of social death and thus that FT can be considered lifesaving. 2 allotransplantation.

show abstract

Breast cancer recurrence after immediate and delayed postmastectomy breast reconstruction—A systematic review and meta‐analysis

Bargon

Young‐Afat

Ikinci

et al. 2022

Cancer

View full text Add to dashboard Cite

BACKGROUND: Oncological safety of different types and timings of PMBR after breast cancer remains controversial. Lack of stratified risk assessment in literature makes current clinical and shared decision-making complex. This is the first systematic review and meta-analysis to evaluate differences in oncological outcomes after immediate versus delayed postmastectomy breast reconstruction (PMBR) for autologous and implant-based PMBR separately. METHODS: A systematic literature search was performed in MEDLINE, Cochrane Library, and Embase. The Cochrane Collaboration Handbook and Meta-analysis Of Observational Studies in Epidemiology checklist were followed for data abstraction. Variability in point estimates attributable to heterogeneity was assessed using I 2 -statistic. (Loco)regional breast cancer recurrence rates, distant metastasis rates, and overall breast cancer recurrence rates were pooled in generalized linear mixed models using random effects. RESULTS: Fifty-five studies, evaluating 14,217 patients, were included. When comparing immediate versus delayed autologous PMBR, weighted average proportions were: 0.03 (95% confidence interval [CI], 0.02-0.03) versus 0.02 (95% CI, 0.01-0.04), respectively, for local recurrences, 0.02 (95% CI, 0.01-0.03) versus 0.02 (95% CI, 0.01-0.03) for regional recurrences, and 0.04 (95% CI, 0.03-0.06) versus 0.01 (95% CI, 0.00-0.03) for locoregional recurrences. No statistically significant differences in weighted average proportions for local, regional and locoregional recurrence rates were observed between immediate and delayed autologous PMBR. Data did not allow comparing weighted average proportions of distant metastases and total breast cancer recurrences after autologous PMBR, and of all outcome measures after implant-based PMBR. CONCLUSIONS: Delayed autologous PMBR leads to similar (loco)regional breast cancer recurrence rates compared to immediate autologous PMBR. This study highlights the paucity of strong evidence on breast cancer recurrence after specific types and timings of PMBR.

show abstract

Patient-Reported Outcome Measures May Add Value in Breast Cancer Surgery

Abstract: PRO scores were associated with age, time since surgery, type of surgery, and radiation therapy in breast cancer patients. The scores serve as a reference value for different types of surgery in the study population and enable prospective use of PROs in shared decision-making.

Cited by 65 publications

References 20 publications

Patient-reported outcome after oncoplastic breast surgery compared with conventional breast-conserving surgery in breast cancer

Patient-reported outcome after oncoplastic breast surgery compared with conventional breast-conserving surgery in breast cancer

How to Integrate Lived Experience Into Quality-of-Life Assessment in Patients Considering Facial Transplantation

Breast cancer recurrence after immediate and delayed postmastectomy breast reconstruction—A systematic review and meta‐analysis

Contact Info

Product

Resources

About