Patient-reported outcome measures for uncomplicated urinary tract infections in women: a systematic review

Abstract

Purpose To conduct a systematic review of the quality of existing patient-reported outcome measures (PROMs) for use in women with uncomplicated urinary tract infections (UTIs) applying the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) methodology, and to derive recommendations for their use in future research. Methods A systematic literature search was performed in PubMed and Web of Science. Studies reporting on the development and/or validation of any PROMs for uncomplicated UTIs in women were considered eligible. We evaluated the methodological quality of each included study using the COSMIN Risk of Bias Checklist, and further applied predefined criteria for good measurement properties. Finally, we graded the evidence and derived recommendations for the use of the included PROMs. Results Data from 23 studies reporting on six PROMs were included. From those, the Acute Cystitis Symptom Score (ACSS) and the Urinary Tract Infection-Symptom and Impairment Questionnaire (UTI-SIQ-8) can be recommended for further use. Both instruments showed sufficient content validity. We further found high-quality evidence for sufficient internal consistency of the UTI-SIQ-8, while this criterion was not assessed for the ACSS due to a formative measurement model. All other PROMs have the potential to be recommended for use, but require further validation. Conclusion The ACSS and the UTI-SIQ-8 have the potential to be recommended for use in women with uncomplicated UTIs in future clinical trials. For all included PROMs, further validation studies are indicated. Systematic review registration: PROSPERO.

Comparative effectiveness of non-pharmacological interventions for primary dysmenorrhea: A protocol for a systematic review and network meta-analysis

“…The copyright holder for this preprint this version posted April 1, 2024. ; https://doi.org/10.1101/2024.03.30.24305112 doi: medRxiv preprint prevalence of PD to be 45% to 95%, with 2% to 29% of menstruating women experiencing severe symptoms. [3][4] Moreover, PD frequently progresses to chronic pain and significantly impacts the daily lives and psychological states of patients to varying extents, [5][6] including problems with work or social activities, stress, anxiety, and depression. PD has been reported as the leading cause of school absenteeism in adolescent girls.…”

Content Validity and Psychometric Properties of the German Version of the Holm and Cordoba Urinary Tract Infection Score for Uncomplicated Urinary Tract Infections in Women: Protocol for a Validation Study

“…A systematic review of the quality of measurement properties of available PROMs for uncomplicated UTIs using the COSMIN methodology was performed [ 11 ]. Among the identified PROMs measuring symptom severity and bothersomeness, the Acute Cystitis Symptom Score (ACSS) [ 6 ] and the Urinary Tract Infection-Symptom and Impairment Questionnaire (UTI-SIQ-8) [ 7 ] can be recommended for use (COSMIN category A).…”