Patient-reported outcome is associated with health care costs in patients with ischaemic heart disease and arrhythmia

Borregaard, Britt; Thrysoee, Lars; Ekholm, Ola

doi:10.1093/eurjcn/zvac030

Cited by 2 publications

(1 citation statement)

References 29 publications

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“…Choroby sercowo-naczyniowe znacznie obciążają budżety systemu zdrowia, a także są główną przyczyną śmiertelności i niepełnosprawności pacjentów. Prognozuje się, że starzenie się społeczeństwa i wzrost liczby pacjentów z przewlekłymi chorobami serca na całym świecie przyczyni się do jeszcze większego pogłębienia tych dysproporcji świecie [35].…”

Section: Choroba Niedokrwienna Sercaunclassified

Multidirectional pharmacological effects of saponins in light of clinical trials: a systematic review of literature

Adam

Rafał

MATYSEK

et al. 2023

J Educ Health Sport

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Introduction: Saponins are secondary metabolites widely distributed in higher plants with multidirectional pharmacological effects. We distinguish between steroidal and triterpenoidal saponins, which are composed of glycone and aglycone. The varied medicinal properties of saponins are influenced by the presence of different substituents in the polycyclic aglycone, e.g. hydroxyls, hydroxymethyls, carboxyls and acyl groups, as well as the difference in bonding, composition and number of sugar chains. It is noteworthy that foods rich in these compounds can reduce the risk of developing various diseases, and the isolation of these compounds from the plant matrix provides new opportunities to create potential and effective drugs. Purpose of the work: Conduct a literature review on the basis of available clinical studies on the pharmacological effects of saponins extracted from medicinal plants and their potential application in medicine. Materials and methods: The work was based on a literature review of available medical publications from clinical trials conducted for the multidirectional therapeutic effects of saponins. Reports available in publications and scientific studies posted in medical information databases such as Pubmed and Google Scholar were summarised. Results: Clinical studies confirm the pharmacological effect of saponins in the treatment of sports injuries and trauma, type II diabetes, abnormal glycemic state fasting glucose, ischemic heart disease, pancytopenia and aplastic anemia. Conclusions: With the advancement of scientific research on saponins, it is possible to use them to produce potential drugs and dietary supplements with pharmacological effects. However, before saponins can be used for medical treatment, further research on their efficacy and safety is needed.

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Section: Choroba Niedokrwienna Sercaunclassified

Multidirectional pharmacological effects of saponins in light of clinical trials: a systematic review of literature

Adam

Rafał

MATYSEK

et al. 2023

J Educ Health Sport

View full text Add to dashboard Cite

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More positive patient-reported outcomes in patients newly diagnosed with atrial fibrillation: a comparative longitudinal study

Holmlund,

Hörnsten,

Hörnsten

et al. 2024

European Journal of Cardiovascular Nursing

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Aims To compare patient-reported outcomes (PROs) in patients newly (< six months) diagnosed with atrial fibrillation (AF) with those who have had the diagnosis longer (≥ six months) and to investigate whether or not these outcomes change over a six month’s period. Methods and results In this longitudinal survey study, 129 patients with AF completed the Revised Illness Perception Questionnaire, the Arrhythmia-Specific questionnaire in Tachycardia and Arrhythmia, and the Hospital Anxiety and Depression Scale at baseline and after six months. At baseline, patients newly diagnosed with AF (n=53), compared to patients with a previous diagnosis (n=76), reported AF as more temporary (P = 0.003) and had higher belief in personal- and treatment control (P = 0.004, P = 0.041 respectively). At six months follow-up, patients newly diagnosed reported a lower symptom burden (P = 0.004), better health-related quality of life (HRQoL) (P = 0.015) and higher personal control (P < 0.001) than patients previously diagnosed. Over time, in patients newly diagnosed, symptom burden and anxiety symptom score decreased (P = 0.001, P = 0.014 respectively) and HRQoL improved (P = 0.002). Conclusions Patients newly diagnosed with AF reported more positive PROs both at baseline and at six months follow-up than patients with a previous diagnosis of AF. Therefore, it is important to quickly capture patients newly diagnosed to support their belief in their own abilities. Such support may, alongside medical treatments, help the patients manage the disease, which may lead to reduced symptom burden and better HRQoL over time.

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Patient-reported outcome is associated with health care costs in patients with ischaemic heart disease and arrhythmia

Cited by 2 publications

References 29 publications

Multidirectional pharmacological effects of saponins in light of clinical trials: a systematic review of literature

Multidirectional pharmacological effects of saponins in light of clinical trials: a systematic review of literature

More positive patient-reported outcomes in patients newly diagnosed with atrial fibrillation: a comparative longitudinal study

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