Patient-related and anesthesia-dependent determinants for postoperative delirium after oral and maxillofacial surgery. Results from a register-based case-control study

Ortner, Florian; Eberl, Marian; Otto, Sven; Wang, Baocheng; Schauberger, Gunther; Hofmann-Kiefer, Klaus; Saller, Thomas

doi:10.1016/j.jormas.2020.04.002

Cited by 5 publications

(3 citation statements)

References 47 publications

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“…Risk of institutionalization postdischarge was higher in patients with DSD compared with PWDs, consistent with a previous review. 69 Common reasons influencing institutionalization of PWDs included poor cognition, neuropsychiatric symptoms, and care dependency. 70e72 As discussed above, patients with DSD experienced poorer cognition than PWDs.…”

Section: Discussionmentioning

confidence: 99%

Prevalence, Risk Factors, and Impact of Delirium on Hospitalized Older Adults With Dementia: A Systematic Review and Meta-Analysis

Han

Rodrigues

Klainin‐Yobas

et al. 2022

Journal of the American Medical Directors Association

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Section: Discussionmentioning

confidence: 99%

Prevalence, Risk Factors, and Impact of Delirium on Hospitalized Older Adults With Dementia: A Systematic Review and Meta-Analysis

Han

Rodrigues

Klainin‐Yobas

et al. 2022

Journal of the American Medical Directors Association

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“…Based on previous clinical studies, the incidence of postoperative delirium was assumed to be 30% in older patients undergoing oral and maxillofacial surgery. 13 A total of 118 randomized patients (1:1, 54 in each group) completed the primary outcome assessment to achieve 80% efficacy with alpha error at 5%. A total of 125 patients were screened for this study, taking 5% drop rate into account.…”

Section: Methodsmentioning

confidence: 99%

“…Patients undergoing oral and maxillofacial surgery were considered to be at high risk of postoperative delirium. 13 Furuya 14 showed that the incidence of delirium after oral and maxillofacial was higher than that of plastic surgery and ear, nose and throat surgery, and similar to that of neurosurgery. Advanced age, postoperative incision swelling and pain, and disturbed sleep cycle were risk factors for delirium.…”

Section: Introductionmentioning

confidence: 97%

Effect of Perioperative Dexmedetomidine Infusion on Postoperative Delirium in Elderly Patients Undergoing Oral and Maxillofacial Surgery: A Randomized Controlled Clinical Trial

Liu¹,

Tuo²,

Wei³

et al. 2022

IJGM

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Purpose The aim of the study was to determine whether perioperative dexmedetomidine administration can improve postoperative delirium in elderly patients undergoing oral and maxillofacial surgery. Patients and Methods This was a prospective double-blind randomized controlled clinical trial conducted in Cangzhou Central Hospital from December 2021 to March 2022. Patients aged 65 and older underwent oral and maxillofacial surgery under general anesthesia. Eligible patients were randomly assigned to dexmedetomidine or control group. Dexmedetomidine was injected intravenously from 10 min before induction of anesthesia to 30 min before the end of surgery in dexmedetomidine group, while patients in the control group were given normal saline at the same rate during the same time period. The primary measurement indicators were the incidence and duration of delirium in the first five days after surgery. The secondary measurement indicators were Visual Analogue Score (VAS) for the first 24 hours following surgery, subjective sleep quality score within 24 hours postoperatively and intraoperative adverse reactions. Results One hundred and twenty patients were randomly assigned. Baseline characteristics were similar between two groups. The incidence and duration of postoperative delirium did not differ statistically between two groups (all P > 0.05). Compared with control group, VAS scores in dexmedetomidine group were significantly lower at 6, 12, and 24 hours after surgery (all P < 0.05); moreover, Richards-Campbell Sleep Questionnaire (RCSQ) results were significantly improved 1 day after surgery in dexmedetomidine group (P < 0.05). Dexmedetomidine-related adverse reactions were similar in both groups (P > 0.05). Conclusion Intravenous infusion of dexmedetomidine 10 min before induction of anesthesia to half an hour before the end of surgery did not improve postoperative delirium in elderly patients undergoing oral and maxillofacial surgery; however, dexmedetomidine may be associated with decreased postoperative pain and improved postoperative sleep quality.

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Perioperative Considerations for Patients with a Known Diagnosis of Dementia

McSwain

Sirianni

Wilson

2021

Advances in Anesthesia

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Patient-related and anesthesia-dependent determinants for postoperative delirium after oral and maxillofacial surgery. Results from a register-based case-control study

Cited by 5 publications

References 47 publications

Prevalence, Risk Factors, and Impact of Delirium on Hospitalized Older Adults With Dementia: A Systematic Review and Meta-Analysis

Prevalence, Risk Factors, and Impact of Delirium on Hospitalized Older Adults With Dementia: A Systematic Review and Meta-Analysis

Effect of Perioperative Dexmedetomidine Infusion on Postoperative Delirium in Elderly Patients Undergoing Oral and Maxillofacial Surgery: A Randomized Controlled Clinical Trial

Perioperative Considerations for Patients with a Known Diagnosis of Dementia

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