Patient refusal of surgery following Innovar premedication

Lee, C. M.; Yeakel, Allen E.

doi:10.1097/00006534-197511000-00084

Cited by 7 publications

(8 citation statements)

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“…It is therefore possible that patients receiving droperidol retain their painful memory of local anesthetic infiltration. It has been reported that droperidol rarely but potentially leads to unidentified panic attacks, even it has been recognized as a useful adjunct to premedication [27]. In our study, all patients who could be followed up to the end of the study did not complain of the unusual physical sensations, restlessness, or nervousness noted in former reports.…”

Section: Discussionsupporting

confidence: 40%

Predominant effects of midazolam for conscious sedation: benefits beyond the early postoperative period

et al. 2010

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Section: Discussionsupporting

confidence: 40%

Predominant effects of midazolam for conscious sedation: benefits beyond the early postoperative period

et al. 2010

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“…Droperidol has an antiemetic potency approximately 800 times greater than that of thorazine (23). Droperidol enhances the sedation provided by nalbuphine and diminishes patient recall of the procedure (18,19).…”

Section: Discussionmentioning

confidence: 99%

Nalbuphine and droperidol in combination for sedation and prevention of nausea and vomiting during intra-carotid BCNU infusion

Klein

Mahaley

1986

J Neuro-Oncol

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A therapeutic regimen is described for sedative, analgesic, and anti-emetic effect in patients receiving intra-arterial carmustine (BCNU) for malignant gliomas. This regimen consists of nalbuphine, 30 mg, i.v., and droperidol, 2.5 mg, i.v., given immediately prior to intra-carotid BCNU infusion. Droperidol, 2.5 mg, i.v., is then administered on four hour intervals for sixteen hours post-procedure. This combination provided excellent effect in nine patients treated for twelve intra-carotid infusions. None of the nine patients experienced vomiting, one experienced mild nausea several hours post-infusion, and non complained of severe pain or discomfort. Thirteen additional patients received diazepam, 10 mg, P.O., prior to the intra-carotid BCNU infusion, with fentanyl, 100 mcg, i.v., and prochlorperazine, 10 mg, i.m. at the onset of infusion. All thirteen patients suffered from severe nausea, vomiting, and orbital pain. The nalbuphine/droperidol combination is thought to provide a superior alternative to the traditional narcotic/pheonothiazine/benzodiazepine combination for carotid BCNU infusion. This combination has theoretical advantages for the patient with intracranial mass lesions by providing analgesia and sedation with minimal potential for respiratory depression and carbon dioxide retention.

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“…Thalamonal®-Prämedikationen die bevorstehende Operation aufgrund von Panikattacken verweigert wurde [4,17,27].Die Anwendung von Droperidol in der Prämedikation wurde wegen dieser negativen Auswirkungen auf die psychische Befindlichkeit der Patienten weitestgehend verlassen.Als Antiemetikum wird Droperidol dagegen immer noch häufig eingesetzt. In der Regel werden dabei Dosierungen von 0,25 mg [20] bis 5 mg [22] in der Prophylaxe und Therapie von postoperativer Übelkeit oder Erbrechen (PONV) eingesetzt.…”

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“…Thalamonal®-Prämedikationen die bevorstehende Operation aufgrund von Panikattacken verweigert wurde [4,17,27].…”

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Einfluß verschiedener niedriger Droperidol-Dosierungen auf postoperative Angst, innere Anspannung, allgemeine Befindlichkeit und PONV

et al. 1999

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Patient refusal of surgery following Innovar premedication

Cited by 7 publications

References 0 publications

Predominant effects of midazolam for conscious sedation: benefits beyond the early postoperative period

Predominant effects of midazolam for conscious sedation: benefits beyond the early postoperative period

Nalbuphine and droperidol in combination for sedation and prevention of nausea and vomiting during intra-carotid BCNU infusion

Einfluß verschiedener niedriger Droperidol-Dosierungen auf postoperative Angst, innere Anspannung, allgemeine Befindlichkeit und PONV

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